CRCGN015_MCF10A.TP53.M_24H:F23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1h-1,2,3-benzotriazole 33.61 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 5.19423
WFS1 Wolfram syndrome 1 (wolframin) 4.7339
CXCR4 chemokine (C-X-C motif) receptor 4 4.5061
PDLIM1 PDZ and LIM domain 1 2.6719
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.56855
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.5559
TRAPPC6A trafficking protein particle complex 6A 2.55135
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.04418

decreased expression

Symbol Name Standardized Value
RPIA ribose 5-phosphate isomerase A -5.03525
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.86172
KRT14 keratin 14, type I -3.2716
RPA3 replication protein A3, 14kDa -3.0916
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.67205
HSPA1A heat shock 70kDa protein 1A -2.46345
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.3376