CRCGN015_MCF10A.TP53.M_24H:G02 Gene Set
Genes
43 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:G02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
METRN
|
meteorin, glial cell differentiation regulator
|
4.55645
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.68803
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
3.67797
|
|
INTS3
|
integrator complex subunit 3
|
3.33367
|
|
IDE
|
insulin-degrading enzyme
|
3.31049
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.70563
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.60341
|
|
FBXO11
|
F-box protein 11
|
2.53045
|
|
FZD1
|
frizzled class receptor 1
|
2.50747
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
2.499
|
|
PYCR1
|
pyrroline-5-carboxylate reductase 1
|
2.42877
|
|
ATP1A3
|
ATPase, Na+/K+ transporting, alpha 3 polypeptide
|
2.42475
|
|
CABYR
|
calcium binding tyrosine-(Y)-phosphorylation regulated
|
2.41174
|
|
SLC1A4
|
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
|
2.38525
|
|
PCSK2
|
proprotein convertase subtilisin/kexin type 2
|
2.37811
|
|
FOXJ3
|
forkhead box J3
|
2.34364
|
|
SNPH
|
syntaphilin
|
2.33107
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
2.31138
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.20131
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
2.13321
|
|
ASNS
|
asparagine synthetase (glutamine-hydrolyzing)
|
2.10726
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.1052
|
|
DNAJB4
|
DnaJ (Hsp40) homolog, subfamily B, member 4
|
2.10067
|
|
VSNL1
|
visinin-like 1
|
2.08268
|
|
UBQLN2
|
ubiquilin 2
|
2.02608
|
|
RPAIN
|
RPA interacting protein
|
2.01958
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.21564
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-3.63314
|
|
HMG20B
|
high mobility group 20B
|
-3.45586
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-3.3264
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.10967
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-3.0827
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.88714
|
|
LYPLA1
|
lysophospholipase I
|
-2.78481
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.7507
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
-2.69856
|
|
RPS5
|
ribosomal protein S5
|
-2.69376
|
|
CYCS
|
cytochrome c, somatic
|
-2.45737
|
|
SIGLEC15
|
sialic acid binding Ig-like lectin 15
|
-2.35542
|
|
AP5M1
|
adaptor-related protein complex 5, mu 1 subunit
|
-2.14557
|
|
SPAG7
|
sperm associated antigen 7
|
-2.10152
|
|
KRT14
|
keratin 14, type I
|
-2.05692
|
|
TMEM132A
|
transmembrane protein 132A
|
-2.02199
|
