| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-chloroacetophenone 33.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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77 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:G08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 5.1929 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 5.15695 |
| CCNA1 | cyclin A1 | 4.9129 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 4.478 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.42185 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 4.36615 |
| SIRT3 | sirtuin 3 | 3.92977 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | 3.51815 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.3806 |
| S1PR4 | sphingosine-1-phosphate receptor 4 | 3.32925 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 3.07702 |
| PKN1 | protein kinase N1 | 3.03165 |
| FZD1 | frizzled class receptor 1 | 2.89272 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 2.69847 |
| SPRR1B | small proline-rich protein 1B | 2.6535 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 2.6366 |
| COQ8A | coenzyme Q8A | 2.4994 |
| DEAF1 | DEAF1 transcription factor | 2.38285 |
| HOXB9 | homeobox B9 | 2.3486 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | 2.34605 |
| LMF1 | lipase maturation factor 1 | 2.33022 |
| SMAGP | small cell adhesion glycoprotein | 2.32995 |
| CERK | ceramide kinase | 2.3076 |
| SATB1 | SATB homeobox 1 | 2.2803 |
| RSF1 | remodeling and spacing factor 1 | 2.2165 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | 2.20625 |
| MXD1 | MAX dimerization protein 1 | 2.19545 |
| CD151 | CD151 molecule (Raph blood group) | 2.1841 |
| TMEM80 | transmembrane protein 80 | 2.1835 |
| CPNE7 | copine VII | 2.17345 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 2.1525 |
| SPRR1A | small proline-rich protein 1A | 2.14302 |
| CLCN5 | chloride channel, voltage-sensitive 5 | 2.1367 |
| BICD2 | bicaudal D homolog 2 (Drosophila) | 2.13645 |
| TRAPPC4 | trafficking protein particle complex 4 | 2.1095 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 2.079 |
| COMP | cartilage oligomeric matrix protein | 2.05955 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 2.0583 |
| ELSPBP1 | epididymal sperm binding protein 1 | 2.0368 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) | 2.0241 |
| SPRR2B | small proline-rich protein 2B | 2.0239 |
| LGALS7B | lectin, galactoside-binding, soluble, 7B | 2.01865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ISOC1 | isochorismatase domain containing 1 | -5.579 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -5.20385 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.9322 |
| DSG2 | desmoglein 2 | -4.4064 |
| HOXA5 | homeobox A5 | -3.776 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -2.8941 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.8541 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.7961 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -2.67777 |
| SNX7 | sorting nexin 7 | -2.66855 |
| CD320 | CD320 molecule | -2.6061 |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 | -2.4822 |
| PRSS23 | protease, serine, 23 | -2.41185 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -2.36797 |
| SCARA3 | scavenger receptor class A, member 3 | -2.3501 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -2.32105 |
| PCDH17 | protocadherin 17 | -2.28215 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -2.26695 |
| RPA3 | replication protein A3, 14kDa | -2.21735 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -2.1874 |
| GFRA1 | GDNF family receptor alpha 1 | -2.18435 |
| CEP70 | centrosomal protein 70kDa | -2.1723 |
| ZNF134 | zinc finger protein 134 | -2.17025 |
| CCL11 | chemokine (C-C motif) ligand 11 | -2.16505 |
| BAG1 | BCL2-associated athanogene | -2.12515 |
| ZNF26 | zinc finger protein 26 | -2.12305 |
| TRIM36 | tripartite motif containing 36 | -2.08795 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | -2.0823 |
| SDF4 | stromal cell derived factor 4 | -2.07503 |
| ZNF667 | zinc finger protein 667 | -2.0566 |
| IFI27 | interferon, alpha-inducible protein 27 | -2.04065 |
| CMTR1 | cap methyltransferase 1 | -2.0328 |
| TGFBR3 | transforming growth factor, beta receptor III | -2.0287 |
| PCDHA9 | protocadherin alpha 9 | -2.01875 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 | -2.0057 |
