CRCGN015_MCF10A.TP53.M_24H:G10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopyrrolidine 105.01 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:G10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.5956
ACAA1 acetyl-CoA acyltransferase 1 3.81903
MMP1 matrix metallopeptidase 1 2.0316

decreased expression

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -5.38205
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.51795
SNCA synuclein, alpha (non A4 component of amyloid precursor) -3.78164
PTK2 protein tyrosine kinase 2 -3.56215
PCCB propionyl CoA carboxylase, beta polypeptide -2.98135
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.63842
GRWD1 glutamate-rich WD repeat containing 1 -2.44635
BASP1 brain abundant, membrane attached signal protein 1 -2.4019
RPA3 replication protein A3, 14kDa -2.1937
PFN1 profilin 1 -2.13635
ATP11B ATPase, class VI, type 11B -2.1315