CRCGN015_MCF10A.TP53.M_24H:G11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopyrrolidine 35.0 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

65 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:G11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 5.03625
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.97447
LGMN legumain 3.66825
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.37932
CNRIP1 cannabinoid receptor interacting protein 1 3.2163
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.9874
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.8528
GLDC glycine dehydrogenase (decarboxylating) 2.73765
NOSIP nitric oxide synthase interacting protein 2.5959
TMEM14A transmembrane protein 14A 2.5604
CAPN1 calpain 1, (mu/I) large subunit 2.4321
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.42975
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.3611
ARF5 ADP-ribosylation factor 5 2.33175
SLC75A1 solute carrier family 75 member 1 2.3204
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.2855
TEX10 testis expressed 10 2.24405
HIP1 huntingtin interacting protein 1 2.20095
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.2003
PECR peroxisomal trans-2-enoyl-CoA reductase 2.16745
HBA1 hemoglobin, alpha 1 2.10187
NKG7 natural killer cell granule protein 7 2.0585
SLC35B1 solute carrier family 35, member B1 2.0516
TIMP4 TIMP metallopeptidase inhibitor 4 2.0226
PUF60 poly-U binding splicing factor 60KDa 2.0133
SELENOW selenoprotein W 2.0

decreased expression

Symbol Name Standardized Value
KDM3A lysine (K)-specific demethylase 3A -6.2631
CD44 CD44 molecule (Indian blood group) -5.08954
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.62305
TNIP1 TNFAIP3 interacting protein 1 -4.33775
GNAS GNAS complex locus -4.29539
CTNND1 catenin (cadherin-associated protein), delta 1 -4.18185
IGFBP7 insulin-like growth factor binding protein 7 -2.83735
SGK1 serum/glucocorticoid regulated kinase 1 -2.8099
PHF10 PHD finger protein 10 -2.5568
APIP APAF1 interacting protein -2.48455
TRIM44 tripartite motif containing 44 -2.43812
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.42388
ATP5F1E ATP synthase F1 subunit epsilon -2.361
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.34675
PRKD3 protein kinase D3 -2.33455
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.31215
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -2.2851
FBXO21 F-box protein 21 -2.24497
KCMF1 potassium channel modulatory factor 1 -2.24325
MAB21L2 mab-21-like 2 (C. elegans) -2.24242
WDR26 WD repeat domain 26 -2.21915
CRHBP corticotropin releasing hormone binding protein -2.19605
TCP11 t-complex 11, testis-specific -2.1507
TMEM242 transmembrane protein 242 -2.1317
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -2.12885
BTG3 BTG family, member 3 -2.10315
LDHA lactate dehydrogenase A -2.09605
PDHX pyruvate dehydrogenase complex, component X -2.0766
RCOR1 REST corepressor 1 -2.05835
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -2.04553
MORC2 MORC family CW-type zinc finger 2 -2.04507
PRM2 protamine 2 -2.0414
VAMP7 vesicle-associated membrane protein 7 -2.03645
FBXO3 F-box protein 3 -2.0364
MTM1 myotubularin 1 -2.02667
BNC1 basonuclin 1 -2.0219
MAN2A1 mannosidase, alpha, class 2A, member 1 -2.01435
MARCO macrophage receptor with collagenous structure -2.00155
THSD1 thrombospondin, type I, domain containing 1 -2.00045