CRCGN015_MCF10A.TP53.M_24H:G12 Gene Set
Genes
46 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:G12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STAP2
|
signal transducing adaptor family member 2
|
5.23085
|
|
SPAG4
|
sperm associated antigen 4
|
4.8117
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.51945
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
4.02798
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
3.41715
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
2.91175
|
|
POU3F2
|
POU class 3 homeobox 2
|
2.8943
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.4563
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
2.34265
|
|
MLST8
|
MTOR associated protein, LST8 homolog (S. cerevisiae)
|
2.26075
|
|
NCKAP1
|
NCK-associated protein 1
|
2.2313
|
|
PSMB1
|
proteasome (prosome, macropain) subunit, beta type, 1
|
2.1986
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
2.1365
|
|
TBL3
|
transducin (beta)-like 3
|
2.1308
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.1168
|
|
RFXAP
|
regulatory factor X-associated protein
|
2.1012
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.07885
|
|
XPO1
|
exportin 1
|
2.05815
|
|
SLC39A4
|
solute carrier family 39 (zinc transporter), member 4
|
2.0486
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.04025
|
|
PNRC1
|
proline-rich nuclear receptor coactivator 1
|
2.0198
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-5.10625
|
|
KIF14
|
kinesin family member 14
|
-4.90055
|
|
TCTA
|
T-cell leukemia translocation altered
|
-4.58785
|
|
CD44
|
CD44 molecule (Indian blood group)
|
-4.13686
|
|
ANXA2
|
annexin A2
|
-3.93782
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-3.53457
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.40255
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.19625
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.8581
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.83175
|
|
RBM34
|
RNA binding motif protein 34
|
-2.82912
|
|
IGFBP7
|
insulin-like growth factor binding protein 7
|
-2.67955
|
|
COQ10B
|
coenzyme Q10 homolog B (S. cerevisiae)
|
-2.4759
|
|
GGPS1
|
geranylgeranyl diphosphate synthase 1
|
-2.41272
|
|
PFN1
|
profilin 1
|
-2.38635
|
|
PHF20L1
|
PHD finger protein 20-like 1
|
-2.32
|
|
GSR
|
glutathione reductase
|
-2.21445
|
|
SOX13
|
SRY (sex determining region Y)-box 13
|
-2.1631
|
|
SLC16A2
|
solute carrier family 16, member 2 (thyroid hormone transporter)
|
-2.1382
|
|
OGFOD1
|
2-oxoglutarate and iron-dependent oxygenase domain containing 1
|
-2.11505
|
|
MSN
|
moesin
|
-2.10915
|
|
PSMD5
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
|
-2.05815
|
|
ATP11B
|
ATPase, class VI, type 11B
|
-2.04755
|
|
CD81
|
CD81 molecule
|
-2.0206
|
|
GATM
|
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
|
-2.00178
|
