CRCGN015_MCF10A.TP53.M_24H:H02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethoxybenzidine.2hcl 33.82 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 4.15942
MICALL1 MICAL-like 1 3.08476
ACAA1 acetyl-CoA acyltransferase 1 3.07932
SNAP25 synaptosomal-associated protein, 25kDa 3.0412
ACLY ATP citrate lyase 3.02662
MYLK myosin light chain kinase 2.61943
RBKS ribokinase 2.53796
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.47349
AGR2 anterior gradient 2 2.36862
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.3465
UGDH UDP-glucose 6-dehydrogenase 2.31024
TBX2 T-box 2 2.10707
INSIG1 insulin induced gene 1 2.04381
IER5 immediate early response 5 2.03765
ALDOC aldolase C, fructose-bisphosphate 2.03384
RPH3A rabphilin 3A 2.03319

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -4.71436
GRWD1 glutamate-rich WD repeat containing 1 -3.31032
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -3.11453
HMG20B high mobility group 20B -3.08882
UFM1 ubiquitin-fold modifier 1 -2.86544
OXCT1 3-oxoacid CoA transferase 1 -2.84179
DCK deoxycytidine kinase -2.66969
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.51191
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.47959
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.40447
PRPF38B pre-mRNA processing factor 38B -2.1958
ADRB2 adrenoceptor beta 2, surface -2.13723
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.00513