| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMBA 33.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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59 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 7.38541 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 6.13757 |
| AGR2 | anterior gradient 2 | 5.6959 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.21719 |
| SPAG4 | sperm associated antigen 4 | 4.11038 |
| GRB10 | growth factor receptor-bound protein 10 | 4.05251 |
| KIF5C | kinesin family member 5C | 3.62756 |
| E2F2 | E2F transcription factor 2 | 3.57365 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 3.06354 |
| MSRA | methionine sulfoxide reductase A | 2.9685 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.94161 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.91692 |
| AXIN1 | axin 1 | 2.91061 |
| FAM222B | family with sequence similarity 222, member B | 2.74575 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.67278 |
| MSH5 | mutS homolog 5 | 2.48465 |
| PLS1 | plastin 1 | 2.44049 |
| ITGA7 | integrin, alpha 7 | 2.43603 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.43242 |
| ACOT13 | acyl-CoA thioesterase 13 | 2.3963 |
| NOSIP | nitric oxide synthase interacting protein | 2.38139 |
| CCNA1 | cyclin A1 | 2.36368 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 2.33557 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 2.3159 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 2.2181 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.18064 |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa | 2.14557 |
| CCDC92 | coiled-coil domain containing 92 | 2.1319 |
| SNRPA1 | small nuclear ribonucleoprotein polypeptide A' | 2.10409 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.07718 |
| BCAS3 | breast carcinoma amplified sequence 3 | 2.04055 |
| KIF14 | kinesin family member 14 | 2.01779 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -5.11014 |
| KIF20A | kinesin family member 20A | -3.69393 |
| TES | testin LIM domain protein | -3.62586 |
| HSPA8 | heat shock 70kDa protein 8 | -3.36533 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.28873 |
| DSG2 | desmoglein 2 | -3.2871 |
| DIPK1A | divergent protein kinase domain 1A | -3.15439 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.95875 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.79506 |
| CHMP4B | charged multivesicular body protein 4B | -2.76526 |
| TCEA2 | transcription elongation factor A (SII), 2 | -2.71625 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.68867 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.54657 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.48663 |
| ILF2 | interleukin enhancer binding factor 2 | -2.48326 |
| NVL | nuclear VCP-like | -2.4828 |
| LRRC41 | leucine rich repeat containing 41 | -2.46372 |
| ISOC1 | isochorismatase domain containing 1 | -2.45036 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -2.37436 |
| GSDMD | gasdermin D | -2.3131 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -2.29934 |
| OMG | oligodendrocyte myelin glycoprotein | -2.25138 |
| HSPA12A | heat shock 70kDa protein 12A | -2.1735 |
| RGS2 | regulator of G-protein signaling 2 | -2.13143 |
| SUSD5 | sushi domain containing 5 | -2.1078 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.10524 |
| GTF2B | general transcription factor IIB | -2.06746 |