CRCGN015_MCF10A.TP53.M_24H:H06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMBA 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WIF1 WNT inhibitory factor 1 3.76759
ADAM10 ADAM metallopeptidase domain 10 3.15438
TOMM34 translocase of outer mitochondrial membrane 34 2.93328
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.77967
MAST2 microtubule associated serine/threonine kinase 2 2.47511
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.45778
AGR2 anterior gradient 2 2.35482
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.18307
EVL Enah/Vasp-like 2.14421
BMP4 bone morphogenetic protein 4 2.1142
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.03133

decreased expression

Symbol Name Standardized Value
YME1L1 YME1-like 1 ATPase -4.24481
GRN granulin -3.83495
UBE3C ubiquitin protein ligase E3C -3.68398
CYCS cytochrome c, somatic -3.52037
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.32503
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.11596
PUF60 poly-U binding splicing factor 60KDa -2.84741
ABI1 abl-interactor 1 -2.60108
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.55165
SLC25A46 solute carrier family 25, member 46 -2.49406
PCNA proliferating cell nuclear antigen -2.28037
SGK1 serum/glucocorticoid regulated kinase 1 -2.0484