CRCGN015_MCF10A.TP53.M_24H:H09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminostilbene 11.15 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 10.0
BZW2 basic leucine zipper and W2 domains 2 5.1692
AGR2 anterior gradient 2 4.857
ADGRE5 adhesion G protein-coupled receptor E5 4.8246
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.81297
KCTD5 potassium channel tetramerization domain containing 5 4.6042
KDM5A lysine (K)-specific demethylase 5A 3.74715
WIF1 WNT inhibitory factor 1 3.73195
ACAA1 acetyl-CoA acyltransferase 1 3.64928
SQOR sulfide quinone oxidoreductase 3.3581
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.8916
GARRE1 granule associated Rac and RHOG effector 1 2.6999
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.6265
TMEM50A transmembrane protein 50A 2.50755
TRAPPC4 trafficking protein particle complex 4 2.35777
PGM1 phosphoglucomutase 1 2.2595
MCUR1 mitochondrial calcium uniporter regulator 1 2.24685
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.13385
ADRB2 adrenoceptor beta 2, surface 2.07905

decreased expression

Symbol Name Standardized Value
RNF167 ring finger protein 167 -5.05485
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.7299
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.72595
NPDC1 neural proliferation, differentiation and control, 1 -4.3506
RALGDS ral guanine nucleotide dissociation stimulator -3.34637
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.71738
ATP11B ATPase, class VI, type 11B -2.5853
BASP1 brain abundant, membrane attached signal protein 1 -2.4876
PFN1 profilin 1 -2.4681
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.3287
CORO1A coronin, actin binding protein, 1A -2.1407
PCDHB6 protocadherin beta 6 -2.0134
PCCB propionyl CoA carboxylase, beta polypeptide -2.0126
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.0123