| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | maleic hydrazide 33.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | 4.9312 |
| EAPP | E2F-associated phosphoprotein | 4.92495 |
| MAMLD1 | mastermind-like domain containing 1 | 4.368 |
| COMP | cartilage oligomeric matrix protein | 4.35655 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 3.817 |
| C5 | complement component 5 | 3.3743 |
| SATB1 | SATB homeobox 1 | 2.67485 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 2.63205 |
| MT1H | metallothionein 1H | 2.5696 |
| SRP54 | signal recognition particle 54kDa | 2.5459 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.53473 |
| DRC9 | dynein regulatory complex subunit 9 | 2.4931 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 2.4899 |
| COPS5 | COP9 signalosome subunit 5 | 2.4843 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.4586 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.4559 |
| NUCB2 | nucleobindin 2 | 2.38285 |
| THYN1 | thymocyte nuclear protein 1 | 2.3814 |
| MT1G | metallothionein 1G | 2.316 |
| ITM2C | integral membrane protein 2C | 2.3018 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 2.28645 |
| MT1F | metallothionein 1F | 2.28347 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | 2.2615 |
| NANS | N-acetylneuraminic acid synthase | 2.26105 |
| DPF2 | D4, zinc and double PHD fingers family 2 | 2.22245 |
| HDAC1 | histone deacetylase 1 | 2.21075 |
| MT1E | metallothionein 1E | 2.18045 |
| RPL30 | ribosomal protein L30 | 2.173 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | 2.1674 |
| RPL34 | ribosomal protein L34 | 2.16715 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 2.14105 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 2.11635 |
| NCOA4 | nuclear receptor coactivator 4 | 2.05935 |
| PRKCH | protein kinase C, eta | 2.05927 |
| RPF1 | ribosome production factor 1 homolog (S. cerevisiae) | 2.0244 |
| GTF2B | general transcription factor IIB | 2.0207 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 2.02017 |
| SHTN1 | shootin 1 | 2.0066 |
| RPL3 | ribosomal protein L3 | 2.00384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -5.0 |
| VAT1 | vesicle amine transport 1 | -4.91985 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -4.60225 |
| PMM2 | phosphomannomutase 2 | -4.36095 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.06685 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -4.00217 |
| VDAC1 | voltage-dependent anion channel 1 | -3.83575 |
| RHOT2 | ras homolog family member T2 | -3.11892 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.9566 |
| HSPA1A | heat shock 70kDa protein 1A | -2.736 |
| SPTB | spectrin, beta, erythrocytic | -2.60893 |
| NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit | -2.59195 |
| RAI14 | retinoic acid induced 14 | -2.5526 |
| MRPL30 | mitochondrial ribosomal protein L30 | -2.5101 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | -2.34255 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -2.31915 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.30775 |
| MTCL1 | microtubule crosslinking factor 1 | -2.28775 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C | -2.2233 |
| CENPT | centromere protein T | -2.20095 |
| COXFA4L2 | cytochrome c oxidase hypoxia associated subunit FA4L2 | -2.14755 |
| CTBP1 | C-terminal binding protein 1 | -2.1106 |
| FAIM | Fas apoptotic inhibitory molecule | -2.0959 |
| IL20RA | interleukin 20 receptor, alpha | -2.0753 |
| CHD8 | chromodomain helicase DNA binding protein 8 | -2.0705 |
| WDR6 | WD repeat domain 6 | -2.06035 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -2.0571 |
| TUFT1 | tuftelin 1 | -2.0339 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -2.02895 |
| FAM50A | family with sequence similarity 50, member A | -2.0125 |
| SNAP91 | synaptosomal-associated protein, 91kDa | -2.01045 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.00695 |
| GDI1 | GDP dissociation inhibitor 1 | -2.0044 |
