CRCGN015_MCF10A.TP53.M_24H:H13 Gene Set
Genes
57 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.25855
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
5.12175
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.51538
|
|
WIF1
|
WNT inhibitory factor 1
|
4.3436
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.63285
|
|
TBX2
|
T-box 2
|
3.43785
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
3.0032
|
|
HBA1
|
hemoglobin, alpha 1
|
2.73903
|
|
HBB
|
hemoglobin, beta
|
2.64173
|
|
HMGA2
|
high mobility group AT-hook 2
|
2.538
|
|
OXCT1
|
3-oxoacid CoA transferase 1
|
2.4825
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.45805
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.39332
|
|
FCHO1
|
FCH domain only 1
|
2.31685
|
|
CETN3
|
centrin, EF-hand protein, 3
|
2.293
|
|
AMZ2
|
archaelysin family metallopeptidase 2
|
2.26095
|
|
SLC6A15
|
solute carrier family 6 (neutral amino acid transporter), member 15
|
2.22695
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
2.17995
|
|
PYCARD
|
PYD and CARD domain containing
|
2.1698
|
|
TMEM50A
|
transmembrane protein 50A
|
2.1694
|
|
NETO2
|
neuropilin (NRP) and tolloid (TLL)-like 2
|
2.1451
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.0685
|
|
FABP4
|
fatty acid binding protein 4, adipocyte
|
2.0684
|
|
POLD4
|
polymerase (DNA-directed), delta 4, accessory subunit
|
2.01835
|
|
CH25H
|
cholesterol 25-hydroxylase
|
2.0147
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
COG2
|
component of oligomeric golgi complex 2
|
-5.12165
|
|
TERF2IP
|
telomeric repeat binding factor 2, interacting protein
|
-4.86565
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.3858
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-4.38205
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-4.11565
|
|
HOXA5
|
homeobox A5
|
-4.0809
|
|
FPGS
|
folylpolyglutamate synthase
|
-3.8298
|
|
INSIG1
|
insulin induced gene 1
|
-2.94242
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.7461
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.7409
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.69095
|
|
RNF139
|
ring finger protein 139
|
-2.45755
|
|
BPGM
|
2,3-bisphosphoglycerate mutase
|
-2.36885
|
|
VPS33B
|
vacuolar protein sorting 33 homolog B (yeast)
|
-2.27705
|
|
EHD1
|
EH-domain containing 1
|
-2.27147
|
|
POLR3B
|
polymerase (RNA) III (DNA directed) polypeptide B
|
-2.22535
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
-2.2249
|
|
BNIP1
|
BCL2/adenovirus E1B 19kDa interacting protein 1
|
-2.21805
|
|
ARFIP2
|
ADP-ribosylation factor interacting protein 2
|
-2.211
|
|
TENM1
|
teneurin transmembrane protein 1
|
-2.18465
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.1491
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-2.111
|
|
DPP6
|
dipeptidyl-peptidase 6
|
-2.09805
|
|
TH
|
tyrosine hydroxylase
|
-2.08825
|
|
NAP1L2
|
nucleosome assembly protein 1-like 2
|
-2.0854
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
-2.0769
|
|
GABARAPL2
|
GABA(A) receptor-associated protein-like 2
|
-2.05985
|
|
KIAA0513
|
KIAA0513
|
-2.04565
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
-2.042
|
|
TMX2
|
thioredoxin-related transmembrane protein 2
|
-2.025
|
|
PRR15L
|
proline rich 15-like
|
-2.02445
|
|
DNM3
|
dynamin 3
|
-2.0094
|
