| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methyl methacrylate 10.94 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 6.1529 |
| SSBP2 | single-stranded DNA binding protein 2 | 5.64815 |
| CDCA4 | cell division cycle associated 4 | 5.60105 |
| GATA3 | GATA binding protein 3 | 4.85442 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.8888 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 3.4807 |
| WIF1 | WNT inhibitory factor 1 | 3.3972 |
| TCTN1 | tectonic family member 1 | 3.28875 |
| TSPAN6 | tetraspanin 6 | 3.192 |
| TBPL1 | TBP-like 1 | 3.17505 |
| NOTCH1 | notch 1 | 3.07805 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 3.0591 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 3.05215 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 2.80595 |
| APOE | apolipoprotein E | 2.76843 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.75327 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 2.72275 |
| MMP1 | matrix metallopeptidase 1 | 2.58572 |
| DENND2D | DENN/MADD domain containing 2D | 2.556 |
| REG1B | regenerating islet-derived 1 beta | 2.5217 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.33605 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.1858 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 2.098 |
| SATB1 | SATB homeobox 1 | 2.06725 |
| GUCY1B1 | guanylate cyclase 1 soluble subunit beta 1 | 2.02093 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 2.00395 |
| SPDEF | SAM pointed domain containing ETS transcription factor | 2.0009 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GTPBP8 | GTP-binding protein 8 (putative) | -5.2563 |
| KRT14 | keratin 14, type I | -4.2412 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -3.75373 |
| MRPL12 | mitochondrial ribosomal protein L12 | -3.75005 |
| LYPLA1 | lysophospholipase I | -3.68193 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.66746 |
| ELAC2 | elaC ribonuclease Z 2 | -3.45655 |
| CAPN2 | calpain 2, (m/II) large subunit | -3.40063 |
| ANKRD10 | ankyrin repeat domain 10 | -2.97165 |
| CAB39 | calcium binding protein 39 | -2.93925 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.83472 |
| HSPA1A | heat shock 70kDa protein 1A | -2.7801 |
| GRN | granulin | -2.7293 |
| SH3D19 | SH3 domain containing 19 | -2.6629 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.55565 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -2.47815 |
| AACS | acetoacetyl-CoA synthetase | -2.4552 |
| PRB3 | proline-rich protein BstNI subfamily 3 | -2.4159 |
| SCAP | SREBF chaperone | -2.2696 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -2.2678 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -2.2462 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -2.2164 |
| MSMO1 | methylsterol monooxygenase 1 | -2.20085 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.1997 |
| PICK1 | protein interacting with PRKCA 1 | -2.1705 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C | -2.1561 |
| CREB1 | cAMP responsive element binding protein 1 | -2.12084 |
| CHPF | chondroitin polymerizing factor | -2.1191 |
| NAXD | NAD(P)HX dehydratase | -2.10425 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | -2.09495 |
| ABHD18 | abhydrolase domain containing 18 | -2.0912 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -2.08725 |
| SMIM29 | small integral membrane protein 29 | -2.05035 |
| SPRR2B | small proline-rich protein 2B | -2.04935 |
| GPS1 | G protein pathway suppressor 1 | -2.04805 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.04625 |
| ANXA8L1 | annexin A8-like 1 | -2.0291 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -2.0202 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | -2.0147 |
