CRCGN015_MCF10A.TP53.M_24H:H19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description estradiol 104.34 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

561 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IL1B interleukin 1, beta 9.33008
CXCL2 chemokine (C-X-C motif) ligand 2 9.06825
UGDH UDP-glucose 6-dehydrogenase 7.4455
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 6.0696
USP6NL USP6 N-terminal like 5.78915
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.44565
CANT1 calcium activated nucleotidase 1 5.4321
IER3 immediate early response 3 5.3972
HBEGF heparin-binding EGF-like growth factor 5.0596
WIF1 WNT inhibitory factor 1 4.98115
EGR1 early growth response 1 4.8566
MAMLD1 mastermind-like domain containing 1 4.74895
STXBP1 syntaxin binding protein 1 4.5521
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.52365
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.34395
CEMIP2 cell migration inducing hyaluronidase 2 4.32635
OXSR1 oxidative stress responsive 1 4.21105
SPAG4 sperm associated antigen 4 4.19475
TNIP1 TNFAIP3 interacting protein 1 4.1351
FOSL1 FOS-like antigen 1 4.07195
HMOX1 heme oxygenase 1 4.01585
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.945
IL1A interleukin 1, alpha 3.8568
TXNRD1 thioredoxin reductase 1 3.78395
SQSTM1 sequestosome 1 3.75248
G0S2 G0/G1 switch 2 3.7096
NUCB2 nucleobindin 2 3.6548
SCCPDH saccharopine dehydrogenase (putative) 3.6415
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 3.60495
FHL2 four and a half LIM domains 2 3.50915
SLC35B1 solute carrier family 35, member B1 3.3879
H2BC12 H2B clustered histone 12 3.38495
TRIB1 tribbles pseudokinase 1 3.3733
NCK2 NCK adaptor protein 2 3.35495
CDPF1 cysteine-rich, DPF motif domain containing 1 3.34795
VEGFC vascular endothelial growth factor C 3.33765
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.2928
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.22815
CTSL cathepsin L 3.178
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.172
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3.13595
MACO1 macoilin 1 2.9954
PLEK2 pleckstrin 2 2.97845
ITPRID2 ITPR interacting domain containing 2 2.9358
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.9159
PDLIM1 PDZ and LIM domain 1 2.8943
PLAUR plasminogen activator, urokinase receptor 2.89202
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 2.8887
CALU calumenin 2.87964
SPAG9 sperm associated antigen 9 2.86517
SEC24A SEC24 family member A 2.863
CHAD chondroadherin 2.8329
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.8299
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.8015
IL6 interleukin 6 2.7957
LIF leukemia inhibitory factor 2.77195
EGR3 early growth response 3 2.7553
LCMT1 leucine carboxyl methyltransferase 1 2.7457
CXCL8 chemokine (C-X-C motif) ligand 8 2.73232
MMP9 matrix metallopeptidase 9 2.7154
CXCL3 chemokine (C-X-C motif) ligand 3 2.70595
MCUR1 mitochondrial calcium uniporter regulator 1 2.69275
ANKRD40 ankyrin repeat domain 40 2.6835
PTHLH parathyroid hormone-like hormone 2.68145
CSNK1E casein kinase 1, epsilon 2.6801
H2BC9 H2B clustered histone 9 2.67775
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.6599
IL11 interleukin 11 2.656
BCORL1 BCL6 corepressor-like 1 2.6545
SH2B3 SH2B adaptor protein 3 2.65315
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 2.63765
GLRX glutaredoxin (thioltransferase) 2.63655
FST follistatin 2.63613
PRAF2 PRA1 domain family, member 2 2.63535
H2BC4 H2B clustered histone 4 2.63497
CLCC1 chloride channel CLIC-like 1 2.63215
H1-2 H1.2 linker histone, cluster member 2.62885
TGFA transforming growth factor, alpha 2.62445
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.62215
CSRP1 cysteine and glycine-rich protein 1 2.62103
DCP1A decapping mRNA 1A 2.6201
KCTD5 potassium channel tetramerization domain containing 5 2.61635
GDI1 GDP dissociation inhibitor 1 2.6061
SIL1 SIL1 nucleotide exchange factor 2.5937
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.57145
TSG101 tumor susceptibility 101 2.55415
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 2.54635
STX4 syntaxin 4 2.53255
MAGED2 melanoma antigen family D2 2.53212
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 2.52205
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.51353
RAP1GAP RAP1 GTPase activating protein 2.5112
DNASE1L1 deoxyribonuclease I-like 1 2.51085
CREB3L2 cAMP responsive element binding protein 3-like 2 2.50745
HYI hydroxypyruvate isomerase (putative) 2.49585
TUBB6 tubulin, beta 6 class V 2.4951
DUSP4 dual specificity phosphatase 4 2.49507
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.4949
SLC39A6 solute carrier family 39 (zinc transporter), member 6 2.49183
MVP major vault protein 2.4818
CDCP1 CUB domain containing protein 1 2.47815
TP53BP2 tumor protein p53 binding protein 2 2.47515
SRSF4 serine/arginine-rich splicing factor 4 2.45945
ALOX12B arachidonate 12-lipoxygenase, 12R type 2.4526
MT1G metallothionein 1G 2.43765
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.43202
LRRC59 leucine rich repeat containing 59 2.4318
TMEM41B transmembrane protein 41B 2.42593
MCFD2 multiple coagulation factor deficiency 2 2.42175
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.41845
BDNF brain-derived neurotrophic factor 2.4143
SPHK1 sphingosine kinase 1 2.3989
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.39843
SH2D2A SH2 domain containing 2A 2.3976
LIMA1 LIM domain and actin binding 1 2.391
TMEM50A transmembrane protein 50A 2.3834
ZC3H12A zinc finger CCCH-type containing 12A 2.3721
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.34795
PRDM4 PR domain containing 4 2.3442
BCAR3 breast cancer anti-estrogen resistance 3 2.3434
ARMCX3 armadillo repeat containing, X-linked 3 2.3425
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.33913
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.3259
SPRY4 sprouty homolog 4 (Drosophila) 2.32545
CSF3 colony stimulating factor 3 (granulocyte) 2.32395
SOX9 SRY (sex determining region Y)-box 9 2.3238
LOC114841035 uncharacterized LOC114841035 2.3133
FICD FIC domain containing 2.3027
LARS1 leucyl-tRNA synthetase 1 2.29995
ZMPSTE24 zinc metallopeptidase STE24 2.29635
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.29215
IL36RN interleukin 36 receptor antagonist 2.2911
HCCS holocytochrome c synthase 2.28885
CD83 CD83 molecule 2.2816
STX11 syntaxin 11 2.28155
RMC1 regulator of MON1-CCZ1 2.27955
MINPP1 multiple inositol-polyphosphate phosphatase 1 2.2686
AXL AXL receptor tyrosine kinase 2.2665
KDM6B lysine (K)-specific demethylase 6B 2.25378
MYH9 myosin, heavy chain 9, non-muscle 2.25335
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.24593
IL22RA1 interleukin 22 receptor, alpha 1 2.24585
FYN FYN proto-oncogene, Src family tyrosine kinase 2.24543
CHIC2 cysteine-rich hydrophobic domain 2 2.24375
C1QL1 complement component 1, q subcomponent-like 1 2.2418
BMP2 bone morphogenetic protein 2 2.24018
ITGAV integrin, alpha V 2.23965
A1CF APOBEC1 complementation factor 2.23335
MXD1 MAX dimerization protein 1 2.21895
OSBPL2 oxysterol binding protein-like 2 2.21438
ASB13 ankyrin repeat and SOCS box containing 13 2.2127
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.21095
USP9X ubiquitin specific peptidase 9, X-linked 2.21088
CAVIN1 caveolae associated protein 1 2.20983
YIPF3 Yip1 domain family, member 3 2.20665
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.2054
JMJD6 jumonji domain containing 6 2.20455
FAT1 FAT atypical cadherin 1 2.20335
MANF mesencephalic astrocyte-derived neurotrophic factor 2.203
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.1995
RGS2 regulator of G-protein signaling 2 2.19695
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.19408
CNN3 calponin 3, acidic 2.19265
ALAS1 5'-aminolevulinate synthase 1 2.19255
AHCTF1 AT hook containing transcription factor 1 2.1872
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.18235
PDIA5 protein disulfide isomerase family A, member 5 2.18135
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.1785
CSNK1A1 casein kinase 1, alpha 1 2.17774
DRAM1 DNA-damage regulated autophagy modulator 1 2.1634
MT1H metallothionein 1H 2.15523
CEP170 centrosomal protein 170kDa 2.15258
JUN jun proto-oncogene 2.14852
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.14165
COL15A1 collagen, type XV, alpha 1 2.14155
IER2 immediate early response 2 2.1363
CARS1 cysteinyl-tRNA synthetase 1 2.13273
STC1 stanniocalcin 1 2.13185
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.13065
DDAH1 dimethylarginine dimethylaminohydrolase 1 2.1256
H2BC5 H2B clustered histone 5 2.1239
CDSN corneodesmosin 2.12103
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.1148
ZFP36 ZFP36 ring finger protein 2.1121
BSDC1 BSD domain containing 1 2.11193
HSPA13 heat shock protein 70kDa family, member 13 2.09328
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.09065
FAM222B family with sequence similarity 222, member B 2.08835
LAMC2 laminin, gamma 2 2.08682
IL36G interleukin 36, gamma 2.0854
FAM168A family with sequence similarity 168, member A 2.07622
EFL1 elongation factor like GTPase 1 2.07605
COPB1 coatomer protein complex, subunit beta 1 2.07365
RAB21 RAB21, member RAS oncogene family 2.0607
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 2.0509
ZBED2 zinc finger, BED-type containing 2 2.05075
PRR36 proline rich 36 2.04935
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.04595
ATXN2 ataxin 2 2.0375
RFTN1 raftlin, lipid raft linker 1 2.0341
GRAMD2B GRAM domain containing 2B 2.03145
H2AC6 H2A clustered histone 6 2.02245
SOWAHC sosondowah ankyrin repeat domain family member C 2.02225
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.00575
PZP pregnancy-zone protein 2.0052
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.00422
DUSP5 dual specificity phosphatase 5 2.00195
CUTA cutA divalent cation tolerance homolog (E. coli) 2.00095

decreased expression

Symbol Name Standardized Value
DDIT4 DNA-damage-inducible transcript 4 -7.0284
DCK deoxycytidine kinase -6.87945
CDK4 cyclin-dependent kinase 4 -6.4771
SCYL3 SCY1-like 3 (S. cerevisiae) -6.32
DERA deoxyribose-phosphate aldolase (putative) -6.2855
ANKRD10 ankyrin repeat domain 10 -6.2281
CDK1 cyclin-dependent kinase 1 -5.93105
PSRC1 proline/serine-rich coiled-coil 1 -5.9061
TOP2A topoisomerase (DNA) II alpha 170kDa -5.88965
CYCS cytochrome c, somatic -5.7615
CRTAP cartilage associated protein -5.2837
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.1773
OXCT1 3-oxoacid CoA transferase 1 -5.1294
CCNB1 cyclin B1 -4.8185
RPS5 ribosomal protein S5 -4.72655
UBE2C ubiquitin-conjugating enzyme E2C -4.6939
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -4.6864
TSC22D3 TSC22 domain family, member 3 -4.66892
CSK c-src tyrosine kinase -4.3513
SYNE2 spectrin repeat containing, nuclear envelope 2 -4.28725
PYGL phosphorylase, glycogen, liver -4.1887
NUSAP1 nucleolar and spindle associated protein 1 -4.184
CENPA centromere protein A -4.15425
TES testin LIM domain protein -4.09447
HOXA5 homeobox A5 -3.99305
SLC35F2 solute carrier family 35, member F2 -3.9814
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.93645
PRR15L proline rich 15-like -3.89665
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.8936
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.88085
HADH hydroxyacyl-CoA dehydrogenase -3.85933
GTPBP8 GTP-binding protein 8 (putative) -3.8289
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.77995
RPA3 replication protein A3, 14kDa -3.752
NLRP4 NLR family, pyrin domain containing 4 -3.74195
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -3.68455
SDHAF3 succinate dehydrogenase complex assembly factor 3 -3.5537
RWDD2B RWD domain containing 2B -3.53765
CDC25B cell division cycle 25B -3.4936
CAPN1 calpain 1, (mu/I) large subunit -3.48865
PLK1 polo-like kinase 1 -3.482
ADRB2 adrenoceptor beta 2, surface -3.46815
CCNB2 cyclin B2 -3.4344
FOXM1 forkhead box M1 -3.3909
ZNF274 zinc finger protein 274 -3.384
RAB25 RAB25, member RAS oncogene family -3.3163
MCM9 minichromosome maintenance complex component 9 -3.26895
AP5M1 adaptor-related protein complex 5, mu 1 subunit -3.2289
ACAA1 acetyl-CoA acyltransferase 1 -3.22668
MCM3 minichromosome maintenance complex component 3 -3.2208
CCNF cyclin F -3.21082
ZDHHC6 zinc finger, DHHC-type containing 6 -3.20435
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.18625
CCNA2 cyclin A2 -3.1791
BIRC5 baculoviral IAP repeat containing 5 -3.15937
DNAL4 dynein, axonemal, light chain 4 -3.15085
AURKB aurora kinase B -3.14785
PIMREG PICALM interacting mitotic regulator -3.11955
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.10875
METTL18 methyltransferase like 18 -3.1085
OVOL2 ovo-like zinc finger 2 -3.0925
TXNDC9 thioredoxin domain containing 9 -3.04192
ADI1 acireductone dioxygenase 1 -3.02165
TP53 tumor protein p53 -3.0075
CIRBP cold inducible RNA binding protein -3.0038
ANXA2 annexin A2 -3.00375
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -3.0031
STMN1 stathmin 1 -2.9957
HMGB2 high mobility group box 2 -2.9844
SETMAR SET domain and mariner transposase fusion gene -2.9824
ESRP1 epithelial splicing regulatory protein 1 -2.96225
NEK2 NIMA-related kinase 2 -2.94298
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.93405
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.92695
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.91905
TCEA2 transcription elongation factor A (SII), 2 -2.91865
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -2.90715
MGMT O-6-methylguanine-DNA methyltransferase -2.8994
PCCB propionyl CoA carboxylase, beta polypeptide -2.8815
DNM1 dynamin 1 -2.8767
BOLA1 bolA family member 1 -2.8741
HMGN3 high mobility group nucleosomal binding domain 3 -2.8721
ETFB electron-transfer-flavoprotein, beta polypeptide -2.87135
CBX3 chromobox homolog 3 -2.85495
MGST2 microsomal glutathione S-transferase 2 -2.85015
TSKU tsukushi, small leucine rich proteoglycan -2.82435
COXFA4 cytochrome c oxidase associated subunit FA4 -2.81715
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -2.8096
MRPL12 mitochondrial ribosomal protein L12 -2.80515
FPGS folylpolyglutamate synthase -2.79265
SKAP2 src kinase associated phosphoprotein 2 -2.79095
TSPAN6 tetraspanin 6 -2.7841
LDHD lactate dehydrogenase D -2.76925
TRAPPC2L trafficking protein particle complex 2-like -2.76715
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.7661
FXN frataxin -2.75125
ARF5 ADP-ribosylation factor 5 -2.74685
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.71975
BAHCC1 BAH domain and coiled-coil containing 1 -2.70335
GALE UDP-galactose-4-epimerase -2.7018
DBF4 DBF4 zinc finger -2.68615
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -2.68035
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.6711
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.66875
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.6682
FBXO5 F-box protein 5 -2.6671
HOXA4 homeobox A4 -2.64685
DSN1 DSN1, MIS12 kinetochore complex component -2.63555
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.62755
IRAK4 interleukin-1 receptor-associated kinase 4 -2.6177
PARPBP PARP1 binding protein -2.61435
COMMD8 COMM domain containing 8 -2.61145
MTG1 mitochondrial ribosome-associated GTPase 1 -2.61045
POT1 protection of telomeres 1 -2.60862
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -2.59945
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.5993
TBC1D10C TBC1 domain family, member 10C -2.5847
RACGAP1 Rac GTPase activating protein 1 -2.57095
EAPP E2F-associated phosphoprotein -2.568
SESN1 sestrin 1 -2.56
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -2.55645
ISOC2 isochorismatase domain containing 2 -2.55095
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -2.545
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.53565
OXA1L oxidase (cytochrome c) assembly 1-like -2.525
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.5188
PAX9 paired box 9 -2.51145
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.4994
FASTK Fas-activated serine/threonine kinase -2.49798
MCRS1 microspherule protein 1 -2.49765
KRT4 keratin 4, type II -2.49645
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -2.49605
MPC1 mitochondrial pyruvate carrier 1 -2.49475
GCDH glutaryl-CoA dehydrogenase -2.48925
TKFC triokinase/FMN cyclase -2.484
AMDHD2 amidohydrolase domain containing 2 -2.48085
WFDC2 WAP four-disulfide core domain 2 -2.47985
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -2.47575
ZNF761 zinc finger protein 761 -2.4725
TLR1 toll-like receptor 1 -2.47165
KIF11 kinesin family member 11 -2.4697
CDCA8 cell division cycle associated 8 -2.4694
KIF4A kinesin family member 4A -2.4643
GTF2A2 general transcription factor IIA, 2, 12kDa -2.46425
DCTN3 dynactin 3 (p22) -2.46195
XPO1 exportin 1 -2.4612
TPPP tubulin polymerization promoting protein -2.4612
SINHCAF SIN3-HDAC complex associated factor -2.45705
HSPB1 heat shock 27kDa protein 1 -2.45125
UPK3B uroplakin 3B -2.4485
ELOVL6 ELOVL fatty acid elongase 6 -2.447
PEX11A peroxisomal biogenesis factor 11 alpha -2.4459
PCIF1 PDX1 C-terminal inhibiting factor 1 -2.44406
PILRB paired immunoglobin-like type 2 receptor beta -2.44
BNC2 basonuclin 2 -2.43945
STK26 serine/threonine protein kinase 26 -2.4371
MLYCD malonyl-CoA decarboxylase -2.43455
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -2.43165
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.4298
SYPL1 synaptophysin-like 1 -2.42115
TMEM126B transmembrane protein 126B -2.41625
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -2.41337
SSH3 slingshot protein phosphatase 3 -2.41
FAM111A family with sequence similarity 111, member A -2.40715
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.40635
TTK TTK protein kinase -2.40325
SLC2A4RG SLC2A4 regulator -2.39665
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.39625
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.39535
BSPRY B-box and SPRY domain containing -2.3948
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.394
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -2.3929
NISCH nischarin -2.38975
PRKCD protein kinase C, delta -2.38885
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.38875
IPCEF1 interaction protein for cytohesin exchange factors 1 -2.3845
PLAC8 placenta-specific 8 -2.3826
COG2 component of oligomeric golgi complex 2 -2.38245
ATP5PO ATP synthase peripheral stalk subunit OSCP -2.38065
NANOS3 nanos homolog 3 (Drosophila) -2.38015
MB myoglobin -2.3792
NLRP2B NLR family pyrin domain containing 2B -2.3763
HOXB3 homeobox B3 -2.3731
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.371
SIDT1 SID1 transmembrane family, member 1 -2.3702
COQ6 coenzyme Q6 monooxygenase -2.36825
MPV17 MpV17 mitochondrial inner membrane protein -2.3651
RAB5C RAB5C, member RAS oncogene family -2.36313
PRC1 protein regulator of cytokinesis 1 -2.36155
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.36015
GRHL2 grainyhead-like 2 (Drosophila) -2.35525
CDKN3 cyclin-dependent kinase inhibitor 3 -2.34615
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.3409
CKMT1A creatine kinase, mitochondrial 1A -2.3332
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.3305
LINS1 lines homolog 1 -2.32905
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -2.3236
KRCC1 lysine-rich coiled-coil 1 -2.3167
DDB2 damage-specific DNA binding protein 2, 48kDa -2.31395
SPTBN2 spectrin, beta, non-erythrocytic 2 -2.3118
PISD phosphatidylserine decarboxylase -2.3048
CSTA cystatin A (stefin A) -2.2962
YEATS4 YEATS domain containing 4 -2.29455
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.28965
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.28965
ATP5PB ATP synthase peripheral stalk-membrane subunit b -2.28865
PLSCR1 phospholipid scramblase 1 -2.28863
RAB5IF RAB5 interacting factor -2.28735
MELK maternal embryonic leucine zipper kinase -2.28615
TRMT5 tRNA methyltransferase 5 -2.27975
LY6D lymphocyte antigen 6 complex, locus D -2.27875
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -2.27415
UNC119B unc-119 homolog B (C. elegans) -2.26845
CEP70 centrosomal protein 70kDa -2.2612
CASC3 cancer susceptibility candidate 3 -2.2611
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -2.25315
PBK PDZ binding kinase -2.25095
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -2.25045
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.24765
KIF15 kinesin family member 15 -2.247
CABIN1 calcineurin binding protein 1 -2.23668
TMEM242 transmembrane protein 242 -2.23485
TROAP trophinin associated protein -2.23105
METTL4 methyltransferase like 4 -2.2264
CYREN cell cycle regulator of NHEJ -2.2262
ZNF134 zinc finger protein 134 -2.22305
TNRC6B trinucleotide repeat containing 6B -2.22115
MBIP MAP3K12 binding inhibitory protein 1 -2.2186
MYNN myoneurin -2.21535
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.20825
RPL39L ribosomal protein L39-like -2.208
DENND1C DENN/MADD domain containing 1C -2.20745
ADA adenosine deaminase -2.20525
NELFB negative elongation factor complex member B -2.20295
HIKESHI heat shock protein nuclear import factor hikeshi -2.1963
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.1944
TMEM168 transmembrane protein 168 -2.1907
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -2.19033
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.18885
ESRP2 epithelial splicing regulatory protein 2 -2.1882
STOML2 stomatin (EPB72)-like 2 -2.18685
H1-10 H1.10 linker histone -2.18
KRT13 keratin 13, type I -2.1773
CCL13 chemokine (C-C motif) ligand 13 -2.1763
EIF1B eukaryotic translation initiation factor 1B -2.1756
MECR mitochondrial trans-2-enoyl-CoA reductase -2.1748
GPR87 G protein-coupled receptor 87 -2.17235
KRABD4 KRAB domain containing 4 -2.17045
CD244 CD244 molecule, natural killer cell receptor 2B4 -2.1703
PRCC papillary renal cell carcinoma (translocation-associated) -2.1684
ZNF544 zinc finger protein 544 -2.1648
METTL1 methyltransferase like 1 -2.1633
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.1607
ATP5F1D ATP synthase F1 subunit delta -2.16045
ZNF571 zinc finger protein 571 -2.1584
LAD1 ladinin 1 -2.1569
HSPA1A heat shock 70kDa protein 1A -2.1566
BPIFA1 BPI fold containing family A, member 1 -2.15625
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.1529
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.1525
TLE2 transducin-like enhancer of split 2 -2.14972
EVL Enah/Vasp-like -2.14955
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.14915
NUP42 nucleoporin 42 -2.14685
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -2.14548
ZNF813 zinc finger protein 813 -2.1351
ERMP1 endoplasmic reticulum metallopeptidase 1 -2.1305
RAD51AP1 RAD51 associated protein 1 -2.1298
CHD3 chromodomain helicase DNA binding protein 3 -2.12822
UGP2 UDP-glucose pyrophosphorylase 2 -2.12785
FAIM Fas apoptotic inhibitory molecule -2.1275
DAPL1 death associated protein-like 1 -2.1242
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.12415
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.1229
UBP1 upstream binding protein 1 (LBP-1a) -2.1204
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine -2.1164
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.11205
BLCAP bladder cancer associated protein -2.1108
GLUL glutamate-ammonia ligase -2.1095
NIPSNAP2 nipsnap homolog 2 -2.1079
HOXA1 homeobox A1 -2.10755
METTL17 methyltransferase like 17 -2.10685
PDCD6 programmed cell death 6 -2.1063
ARRB1 arrestin, beta 1 -2.10489
EML3 echinoderm microtubule associated protein like 3 -2.10352
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.10148
INTS15 integrator complex subunit 15 -2.09812
EPHA1 EPH receptor A1 -2.09725
CGRRF1 cell growth regulator with ring finger domain 1 -2.0953
ZNF518A zinc finger protein 518A -2.09445
TRIM16 tripartite motif containing 16 -2.09405
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.09125
BRIX1 BRX1, biogenesis of ribosomes -2.0883
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -2.08685
TMEM38B transmembrane protein 38B -2.08325
MSMO1 methylsterol monooxygenase 1 -2.08045
GEMIN2 gem (nuclear organelle) associated protein 2 -2.07931
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.0774
SLC38A6 solute carrier family 38, member 6 -2.0735
LDAH lipid droplet associated hydrolase -2.0729
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.0716
GPS1 G protein pathway suppressor 1 -2.0698
MDH1 malate dehydrogenase 1, NAD (soluble) -2.06925
GLRX5 glutaredoxin 5 -2.06715
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.06685
NSUN5 NOP2/Sun domain family, member 5 -2.06507
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.0636
ZNF35 zinc finger protein 35 -2.06185
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.06163
FES FES proto-oncogene, tyrosine kinase -2.06095
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.05925
THOC7 THO complex 7 -2.05915
CGREF1 cell growth regulator with EF-hand domain 1 -2.05705
DENND4B DENN/MADD domain containing 4B -2.0543
ZMYM1 zinc finger, MYM-type 1 -2.0491
H2AZ1 H2A.Z variant histone 1 -2.04897
ADNP activity-dependent neuroprotector homeobox -2.0434
RMI1 RecQ mediated genome instability 1 -2.04285
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.04235
ANKRD49 ankyrin repeat domain 49 -2.04105
ARMC7 armadillo repeat containing 7 -2.04035
SCGB1D1 secretoglobin, family 1D, member 1 -2.039
COMMD1 copper metabolism (Murr1) domain containing 1 -2.0383
PEX11B peroxisomal biogenesis factor 11 beta -2.03745
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.0366
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.03575
LOC102724023 ES1 protein homolog, mitochondrial -2.02983
CD58 CD58 molecule -2.0292
RPS12 ribosomal protein S12 -2.02535
MUC1 mucin 1, cell surface associated -2.02498
CDK3 cyclin-dependent kinase 3 -2.02435
FOCAD focadhesin -2.02385
PUM2 pumilio RNA-binding family member 2 -2.02352
FZD4 frizzled class receptor 4 -2.0235
TLR4 toll-like receptor 4 -2.023
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.0226
C2CD5 C2 calcium-dependent domain containing 5 -2.02125
NFIL3 nuclear factor, interleukin 3 regulated -2.02065
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 -2.0206
CA9 carbonic anhydrase IX -2.01865
MKKS McKusick-Kaufman syndrome -2.01825
CCDC91 coiled-coil domain containing 91 -2.0158
DCAF17 DDB1 and CUL4 associated factor 17 -2.01225
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.0119
S100A2 S100 calcium binding protein A2 -2.0099
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.0096
PRMT1 protein arginine methyltransferase 1 -2.00865
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -2.0085
PCP4 Purkinje cell protein 4 -2.00835
TMEM14A transmembrane protein 14A -2.0077
DEK DEK proto-oncogene -2.00625
ASF1B anti-silencing function 1B histone chaperone -2.00585
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.00095