CRCGN015_MCF10A.TP53.M_24H:H20 Gene Set
Genes
37 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHL21
|
kelch-like family member 21
|
4.695
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.57065
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
4.2882
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.59142
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
2.88635
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
2.7898
|
|
CCNF
|
cyclin F
|
2.2527
|
|
CDK8
|
cyclin-dependent kinase 8
|
2.2496
|
|
HOXA5
|
homeobox A5
|
2.2194
|
|
NOTCH1
|
notch 1
|
2.18525
|
|
GLDC
|
glycine dehydrogenase (decarboxylating)
|
2.13285
|
|
PPIP5K2
|
diphosphoinositol pentakisphosphate kinase 2
|
2.11055
|
|
CCNA1
|
cyclin A1
|
2.0968
|
|
STXBP3
|
syntaxin binding protein 3
|
2.08355
|
|
HIGD1A
|
HIG1 hypoxia inducible domain family, member 1A
|
2.05538
|
|
STAMBP
|
STAM binding protein
|
2.01175
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
STXBP2
|
syntaxin binding protein 2
|
-5.37405
|
|
KIF20A
|
kinesin family member 20A
|
-5.18055
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.40937
|
|
LYPLA1
|
lysophospholipase I
|
-3.47473
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
-3.3485
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-3.13195
|
|
FPGS
|
folylpolyglutamate synthase
|
-2.63225
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.5889
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-2.55097
|
|
WAC
|
WW domain containing adaptor with coiled-coil
|
-2.45113
|
|
GGT5
|
gamma-glutamyltransferase 5
|
-2.38135
|
|
SIL1
|
SIL1 nucleotide exchange factor
|
-2.3661
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.3141
|
|
NEIL1
|
nei endonuclease VIII-like 1 (E. coli)
|
-2.2438
|
|
INTS5
|
integrator complex subunit 5
|
-2.21105
|
|
ZNF768
|
zinc finger protein 768
|
-2.15105
|
|
CDH15
|
cadherin 15, type 1, M-cadherin (myotubule)
|
-2.15057
|
|
SEMA6C
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
|
-2.10795
|
|
OR51E2
|
olfactory receptor, family 51, subfamily E, member 2
|
-2.06255
|
|
GRINA
|
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
|
-2.0471
|
|
MTHFSD
|
methenyltetrahydrofolate synthetase domain containing
|
-2.04355
|
