CRCGN015_MCF10A.TP53.M_24H:H24 Gene Set
Genes
58 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:H24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
5.4404
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
5.0
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
4.7187
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.68266
|
|
CDCA4
|
cell division cycle associated 4
|
4.6126
|
|
PRKCQ
|
protein kinase C, theta
|
4.22285
|
|
HYOU1
|
hypoxia up-regulated 1
|
4.15465
|
|
COMP
|
cartilage oligomeric matrix protein
|
4.02905
|
|
WIF1
|
WNT inhibitory factor 1
|
3.976
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
3.7657
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.6777
|
|
NUCB2
|
nucleobindin 2
|
3.1175
|
|
CEPT1
|
choline/ethanolamine phosphotransferase 1
|
2.6811
|
|
PYCR1
|
pyrroline-5-carboxylate reductase 1
|
2.6133
|
|
PTK2
|
protein tyrosine kinase 2
|
2.59
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.4385
|
|
RNF123
|
ring finger protein 123
|
2.40535
|
|
CNNM3
|
cyclin and CBS domain divalent metal cation transport mediator 3
|
2.395
|
|
EIF5AL1
|
eukaryotic translation initiation factor 5A-like 1
|
2.15625
|
|
RBBP5
|
retinoblastoma binding protein 5
|
2.15445
|
|
CHPF
|
chondroitin polymerizing factor
|
2.14145
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.13455
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
2.11385
|
|
MTA2
|
metastasis associated 1 family, member 2
|
2.0871
|
|
MAGT1
|
magnesium transporter 1
|
2.06475
|
|
FOXO3
|
forkhead box O3
|
2.05915
|
|
MDM4
|
MDM4, p53 regulator
|
2.0506
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.0291
|
|
SSR3
|
signal sequence receptor, gamma (translocon-associated protein gamma)
|
2.00845
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC45
|
cell division cycle 45
|
-4.9397
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.80615
|
|
HMG20B
|
high mobility group 20B
|
-4.75667
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.67185
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
-3.68085
|
|
THAP11
|
THAP domain containing 11
|
-3.42165
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-3.07595
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-3.02253
|
|
CDC25B
|
cell division cycle 25B
|
-2.81765
|
|
IER3
|
immediate early response 3
|
-2.76605
|
|
TBCB
|
tubulin folding cofactor B
|
-2.75372
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.43215
|
|
IL4R
|
interleukin 4 receptor
|
-2.4014
|
|
CXCR2
|
chemokine (C-X-C motif) receptor 2
|
-2.34
|
|
PDCD5
|
programmed cell death 5
|
-2.2773
|
|
MFSD12
|
major facilitator superfamily domain containing 12
|
-2.25253
|
|
UQCR10
|
ubiquinol-cytochrome c reductase, complex III subunit X
|
-2.2447
|
|
GPATCH1
|
G patch domain containing 1
|
-2.23585
|
|
DHX38
|
DEAH (Asp-Glu-Ala-His) box polypeptide 38
|
-2.2347
|
|
IL36G
|
interleukin 36, gamma
|
-2.2317
|
|
DLL3
|
delta-like 3 (Drosophila)
|
-2.2161
|
|
CAPNS1
|
calpain, small subunit 1
|
-2.18955
|
|
TSPAN3
|
tetraspanin 3
|
-2.17467
|
|
FFAR2
|
free fatty acid receptor 2
|
-2.15505
|
|
FRK
|
fyn-related Src family tyrosine kinase
|
-2.1113
|
|
HSPA2
|
heat shock 70kDa protein 2
|
-2.07195
|
|
TMEM147
|
transmembrane protein 147
|
-2.0422
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.02035
|
|
CERS1
|
ceramide synthase 1
|
-2.01745
|
