CRCGN015_MCF10A.TP53.M_24H:I01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 99.96 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 3.68427
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.52906
ZNF586 zinc finger protein 586 3.19219
AXIN1 axin 1 3.17156
HOXA10 homeobox A10 2.81546
SYNE2 spectrin repeat containing, nuclear envelope 2 2.65764
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.6548
SNX11 sorting nexin 11 2.5602
ZNF134 zinc finger protein 134 2.27745
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.21179
RNPS1 RNA binding protein S1, serine-rich domain 2.16393

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -6.31375
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.36296
PCCB propionyl CoA carboxylase, beta polypeptide -3.34522
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.13518
CCDC86 coiled-coil domain containing 86 -2.81624
ANXA2 annexin A2 -2.49747
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.41178
TMEM156 transmembrane protein 156 -2.16643
CCNB2 cyclin B2 -2.166
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 -2.11281
CORO1A coronin, actin binding protein, 1A -2.01201