CRCGN015_MCF10A.TP53.M_24H:I02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 33.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

62 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KDM5A lysine (K)-specific demethylase 5A 3.85104
FKBP14 FK506 binding protein 14, 22 kDa 3.79783
DERA deoxyribose-phosphate aldolase (putative) 3.76532
ECD ecdysoneless homolog (Drosophila) 3.67173
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.53481
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.41434
SPAG4 sperm associated antigen 4 3.26676
MAMLD1 mastermind-like domain containing 1 3.26458
NUP133 nucleoporin 133kDa 3.10008
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.02476
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.95564
STK10 serine/threonine kinase 10 2.8183
LGMN legumain 2.80166
DENND2D DENN/MADD domain containing 2D 2.78349
MOK MOK protein kinase 2.78136
NOSIP nitric oxide synthase interacting protein 2.68635
LYN LYN proto-oncogene, Src family tyrosine kinase 2.66239
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.56121
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.55965
GSK3B glycogen synthase kinase 3 beta 2.49058
SRFBP1 serum response factor binding protein 1 2.42793
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.38859
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.36706
NINJ2 ninjurin 2 2.32082
MAP7 microtubule-associated protein 7 2.30466
SQOR sulfide quinone oxidoreductase 2.2505
AGBL2 ATP/GTP binding protein-like 2 2.22094
PRR7 proline rich 7 (synaptic) 2.20031
AQP9 aquaporin 9 2.19646
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 2.19631
CCL2 chemokine (C-C motif) ligand 2 2.18495
BCL2 B-cell CLL/lymphoma 2 2.18454
PRM2 protamine 2 2.14934
COMP cartilage oligomeric matrix protein 2.14849
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 2.09018
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 2.06849
SLC6A16 solute carrier family 6, member 16 2.03508
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.03246
RIBC2 RIB43A domain with coiled-coils 2 2.0241
PCYOX1 prenylcysteine oxidase 1 2.02074
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 2.016
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.01068

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -4.13549
PCNA proliferating cell nuclear antigen -3.86028
DYNLT3 dynein, light chain, Tctex-type 3 -3.73253
SLC35F2 solute carrier family 35, member F2 -3.52384
HMG20B high mobility group 20B -3.29515
LDHD lactate dehydrogenase D -2.93202
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.78527
PDCL3 phosducin-like 3 -2.64821
ENOPH1 enolase-phosphatase 1 -2.58879
CLTB clathrin, light chain B -2.43192
CCNB1 cyclin B1 -2.41377
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.41061
COG7 component of oligomeric golgi complex 7 -2.41019
DSG2 desmoglein 2 -2.35047
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.33503
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.31783
PMM2 phosphomannomutase 2 -2.2547
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -2.09795
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.0232
RPA3 replication protein A3, 14kDa -2.00063