| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | monoethylhexylphthalate 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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254 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 6.61138 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 5.50965 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.48372 |
| STK10 | serine/threonine kinase 10 | 5.3531 |
| MAMLD1 | mastermind-like domain containing 1 | 5.11619 |
| SSBP2 | single-stranded DNA binding protein 2 | 5.01447 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.94602 |
| BCL7B | B-cell CLL/lymphoma 7B | 4.65969 |
| PLP1 | proteolipid protein 1 | 4.55236 |
| STMN2 | stathmin 2 | 4.40361 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.24279 |
| AGR2 | anterior gradient 2 | 3.972 |
| VGLL4 | vestigial-like family member 4 | 3.77241 |
| KIF5C | kinesin family member 5C | 3.76817 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 3.70519 |
| GATA3 | GATA binding protein 3 | 3.69326 |
| TBC1D16 | TBC1 domain family, member 16 | 3.40267 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 3.36863 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 3.34029 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 3.25245 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 3.1633 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.14821 |
| CETN3 | centrin, EF-hand protein, 3 | 3.14301 |
| PRR7 | proline rich 7 (synaptic) | 3.11481 |
| PBK | PDZ binding kinase | 3.0474 |
| PMP2 | peripheral myelin protein 2 | 3.00938 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.99026 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 2.98595 |
| KDM5D | lysine (K)-specific demethylase 5D | 2.93585 |
| CCNG1 | cyclin G1 | 2.90265 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 2.88392 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 2.86758 |
| CAPN7 | calpain 7 | 2.86145 |
| DEPDC1 | DEP domain containing 1 | 2.84281 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.83906 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 2.77261 |
| OLFM1 | olfactomedin 1 | 2.77084 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 2.73898 |
| UFSP2 | UFM1-specific peptidase 2 | 2.71372 |
| MICALL1 | MICAL-like 1 | 2.66362 |
| TLR5 | toll-like receptor 5 | 2.62657 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 2.61839 |
| ERCC1 | excision repair cross-complementation group 1 | 2.61563 |
| NEFL | neurofilament, light polypeptide | 2.60345 |
| RAB20 | RAB20, member RAS oncogene family | 2.5698 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 2.56865 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 2.55922 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | 2.5589 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 2.55854 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | 2.54979 |
| BAHD1 | bromo adjacent homology domain containing 1 | 2.54614 |
| ZIC1 | Zic family member 1 | 2.52943 |
| CCDC186 | coiled-coil domain containing 186 | 2.52605 |
| SV2B | synaptic vesicle glycoprotein 2B | 2.52492 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 | 2.51572 |
| GPM6B | glycoprotein M6B | 2.51306 |
| LRRN3 | leucine rich repeat neuronal 3 | 2.50747 |
| FER | fer (fps/fes related) tyrosine kinase | 2.50076 |
| NANS | N-acetylneuraminic acid synthase | 2.4685 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 2.45238 |
| GSTT2B | glutathione S-transferase theta 2B (gene/pseudogene) | 2.45208 |
| WDR37 | WD repeat domain 37 | 2.45079 |
| FEV | FEV (ETS oncogene family) | 2.44341 |
| PHACTR1 | phosphatase and actin regulator 1 | 2.4408 |
| QTMAN | queuosine-tRNA mannosyltransferase | 2.43327 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 2.41631 |
| PER1 | period circadian clock 1 | 2.41272 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 2.40874 |
| STAC | SH3 and cysteine rich domain | 2.39622 |
| TLE3 | transducin-like enhancer of split 3 | 2.38032 |
| DCX | doublecortin | 2.36793 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) | 2.3676 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | 2.3596 |
| RBM5 | RNA binding motif protein 5 | 2.35457 |
| ZNF589 | zinc finger protein 589 | 2.35427 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 2.35261 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 | 2.35065 |
| FRG1 | FSHD region gene 1 | 2.34257 |
| SCG3 | secretogranin III | 2.29822 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 2.29586 |
| ZNF571 | zinc finger protein 571 | 2.289 |
| XPC | xeroderma pigmentosum, complementation group C | 2.28275 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 2.27117 |
| CTTN | cortactin | 2.27017 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 2.26383 |
| JAM2 | junctional adhesion molecule 2 | 2.25569 |
| PI15 | peptidase inhibitor 15 | 2.25172 |
| ZWILCH | zwilch kinetochore protein | 2.24284 |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 2.22901 |
| MNT | MAX network transcriptional repressor | 2.22593 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 2.22087 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | 2.20856 |
| CORO7-PAM16 | CORO7-PAM16 readthrough | 2.20691 |
| LMCD1 | LIM and cysteine-rich domains 1 | 2.20679 |
| HMBOX1 | homeobox containing 1 | 2.20101 |
| UIMC1 | ubiquitin interaction motif containing 1 | 2.19846 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | 2.18599 |
| CCNA1 | cyclin A1 | 2.17782 |
| ATP12A | ATPase, H+/K+ transporting, nongastric, alpha polypeptide | 2.1755 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 2.1744 |
| NCAN | neurocan | 2.16904 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | 2.16583 |
| KARS1 | lysyl-tRNA synthetase 1 | 2.16134 |
| XYLT1 | xylosyltransferase I | 2.15435 |
| SEZ6L | seizure related 6 homolog (mouse)-like | 2.15088 |
| NEFM | neurofilament, medium polypeptide | 2.14945 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 2.14076 |
| FBXO11 | F-box protein 11 | 2.13975 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 2.13679 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated | 2.13668 |
| NELL1 | NEL-like 1 (chicken) | 2.13414 |
| RPL29 | ribosomal protein L29 | 2.13319 |
| LOC127933115 | uncharacterized LOC127933115 | 2.13263 |
| BCAN | brevican | 2.12692 |
| EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 | 2.12685 |
| INKA2 | inka box actin regulator 2 | 2.12528 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | 2.11098 |
| CLASP2 | cytoplasmic linker associated protein 2 | 2.07976 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | 2.07508 |
| ATP13A2 | ATPase type 13A2 | 2.07106 |
| LUM | lumican | 2.05828 |
| RGS7 | regulator of G-protein signaling 7 | 2.04835 |
| TRIM9 | tripartite motif containing 9 | 2.0382 |
| LOC102723713 | TP53-target gene 3 protein | 2.0381 |
| SLC5A7 | solute carrier family 5 (sodium/choline cotransporter), member 7 | 2.02652 |
| TSPAN31 | tetraspanin 31 | 2.02221 |
| LRRC20 | leucine rich repeat containing 20 | 2.02152 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.01415 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 2.00976 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.00564 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35F2 | solute carrier family 35, member F2 | -5.45887 |
| PUF60 | poly-U binding splicing factor 60KDa | -5.21477 |
| MPC2 | mitochondrial pyruvate carrier 2 | -5.14657 |
| PMM2 | phosphomannomutase 2 | -5.05295 |
| UFM1 | ubiquitin-fold modifier 1 | -4.94892 |
| RPIA | ribose 5-phosphate isomerase A | -4.88755 |
| PGAM4 | phosphoglycerate mutase family member 4 | -4.80616 |
| S100A8 | S100 calcium binding protein A8 | -4.79588 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -4.79442 |
| BAG3 | BCL2-associated athanogene 3 | -4.71344 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | -4.71189 |
| TRAPPC3 | trafficking protein particle complex 3 | -4.44926 |
| ATF5 | activating transcription factor 5 | -4.26783 |
| DNM1L | dynamin 1-like | -4.18941 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -4.15332 |
| MRPS15 | mitochondrial ribosomal protein S15 | -4.04812 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -3.83181 |
| MRPS31 | mitochondrial ribosomal protein S31 | -3.77991 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -3.75779 |
| MTRF1 | mitochondrial translational release factor 1 | -3.60955 |
| KDM5C | lysine (K)-specific demethylase 5C | -3.50638 |
| SCRIB | scribbled planar cell polarity protein | -3.39349 |
| IPO13 | importin 13 | -3.16198 |
| MICB | MHC class I polypeptide-related sequence B | -3.07448 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.97907 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -2.93985 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -2.91733 |
| RUSC2 | RUN and SH3 domain containing 2 | -2.8815 |
| SOD1 | superoxide dismutase 1, soluble | -2.87778 |
| CFAP298 | cilia and flagella associated protein 298 | -2.79402 |
| IL18 | interleukin 18 | -2.7634 |
| CDK8 | cyclin-dependent kinase 8 | -2.75726 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -2.72285 |
| AMOTL2 | angiomotin like 2 | -2.71889 |
| TOR1A | torsin family 1, member A (torsin A) | -2.66182 |
| MFF | mitochondrial fission factor | -2.63345 |
| DGAT1 | diacylglycerol O-acyltransferase 1 | -2.63252 |
| CD1D | CD1d molecule | -2.61034 |
| RXYLT1 | ribitol xylosyltransferase 1 | -2.60602 |
| REV1 | REV1, polymerase (DNA directed) | -2.58124 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | -2.5712 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.56858 |
| EPHA2 | EPH receptor A2 | -2.55977 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.55385 |
| FZD10 | frizzled class receptor 10 | -2.55371 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.55234 |
| DPP3 | dipeptidyl-peptidase 3 | -2.53518 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.53324 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -2.50214 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.49136 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -2.47957 |
| NAA60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit | -2.47862 |
| NINJ2 | ninjurin 2 | -2.47649 |
| KRT81 | keratin 81, type II | -2.46999 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | -2.46971 |
| SMC1A | structural maintenance of chromosomes 1A | -2.45398 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -2.4456 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 | -2.42424 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -2.40862 |
| KCNG2 | potassium channel, voltage gated modifier subfamily G, member 2 | -2.40808 |
| COL17A1 | collagen, type XVII, alpha 1 | -2.40162 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | -2.39548 |
| LY6G6F-LY6G6D | LY6G6F-LY6G6D readthrough | -2.39274 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -2.38687 |
| SCPEP1 | serine carboxypeptidase 1 | -2.38676 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | -2.38367 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -2.31916 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -2.31666 |
| H2BC5 | H2B clustered histone 5 | -2.30705 |
| SLC38A10 | solute carrier family 38, member 10 | -2.29891 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | -2.28536 |
| NUDC | nudC nuclear distribution protein | -2.28201 |
| CDA | cytidine deaminase | -2.27576 |
| ZNF7 | zinc finger protein 7 | -2.27138 |
| GLB1L2 | galactosidase, beta 1-like 2 | -2.2535 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | -2.25279 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | -2.24596 |
| MSN | moesin | -2.23487 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -2.23091 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -2.22062 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.20417 |
| NFYB | nuclear transcription factor Y, beta | -2.20135 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.20068 |
| FNDC3B | fibronectin type III domain containing 3B | -2.19776 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -2.19211 |
| H2BC9 | H2B clustered histone 9 | -2.182 |
| COL8A2 | collagen, type VIII, alpha 2 | -2.18026 |
| MPO | myeloperoxidase | -2.16645 |
| NKX2-5 | NK2 homeobox 5 | -2.15956 |
| PRPF38B | pre-mRNA processing factor 38B | -2.15187 |
| CYBC1 | cytochrome b-245 chaperone 1 | -2.14667 |
| CD200 | CD200 molecule | -2.13796 |
| PRR13 | proline rich 13 | -2.13364 |
| BPGM | 2,3-bisphosphoglycerate mutase | -2.12779 |
| HSF1 | heat shock transcription factor 1 | -2.12692 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -2.12542 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -2.12258 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.11022 |
| CD1E | CD1e molecule | -2.09874 |
| AIFM2 | apoptosis-inducing factor, mitochondrion-associated, 2 | -2.09386 |
| BOP1 | block of proliferation 1 | -2.08432 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.07687 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -2.06992 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -2.06698 |
| AOAH | acyloxyacyl hydrolase (neutrophil) | -2.06465 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -2.06392 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | -2.06112 |
| LYPD1 | LY6/PLAUR domain containing 1 | -2.06066 |
| IPO8 | importin 8 | -2.05554 |
| STK38 | serine/threonine kinase 38 | -2.05491 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -2.05422 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | -2.04811 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -2.0436 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) | -2.03904 |
| BMP8B | bone morphogenetic protein 8b | -2.02941 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | -2.02829 |
| THOC6 | THO complex 6 | -2.0259 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -2.02211 |
| PBLD | phenazine biosynthesis-like protein domain containing | -2.01773 |
| RRAGC | Ras-related GTP binding C | -2.01562 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 | -2.004 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -2.00259 |
| H2AX | H2A.X variant histone | -2.0021 |
| CDCA8 | cell division cycle associated 8 | -2.00159 |
