CRCGN015_MCF10A.TP53.M_24H:I06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description monoethylhexylphthalate 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MCOLN1 mucolipin 1 4.65378
ABHD4 abhydrolase domain containing 4 4.2434
CARMIL1 capping protein regulator and myosin 1 linker 1 4.00489
INTS3 integrator complex subunit 3 3.91106
CCP110 centriolar coiled coil protein 110kDa 3.46707
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.05387
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.87121
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.71674
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.46275
KCTD5 potassium channel tetramerization domain containing 5 2.46149
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.39242
VGLL4 vestigial-like family member 4 2.34007
ACAA1 acetyl-CoA acyltransferase 1 2.28349
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.10266
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 2.0542
METRN meteorin, glial cell differentiation regulator 2.01205

decreased expression

Symbol Name Standardized Value
TIMP1 TIMP metallopeptidase inhibitor 1 -3.82015
ANXA2 annexin A2 -3.09007
CANT1 calcium activated nucleotidase 1 -2.86679
HMG20B high mobility group 20B -2.46901
STK25 serine/threonine kinase 25 -2.39868
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.36244
NLRP4 NLR family, pyrin domain containing 4 -2.13214