CRCGN015_MCF10A.TP53.M_24H:I09 Gene Set
Genes
34 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
4.97185
|
|
KLHL21
|
kelch-like family member 21
|
4.8999
|
|
COMP
|
cartilage oligomeric matrix protein
|
4.14205
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.09355
|
|
SLC25A14
|
solute carrier family 25 (mitochondrial carrier, brain), member 14
|
3.86268
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
3.7173
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.60357
|
|
COG2
|
component of oligomeric golgi complex 2
|
2.89705
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.55355
|
|
MMP1
|
matrix metallopeptidase 1
|
2.30052
|
|
MXRA8
|
matrix-remodelling associated 8
|
2.2516
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.25095
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.19695
|
|
BNC2
|
basonuclin 2
|
2.19425
|
|
TLCD3A
|
TLC domain containing 3A
|
2.17235
|
|
DVL3
|
dishevelled segment polarity protein 3
|
2.0855
|
|
YJU2B
|
YJU2 splicing factor homolog B
|
2.0625
|
|
MCCC1
|
methylcrotonoyl-CoA carboxylase 1 (alpha)
|
2.0621
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
2.03485
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMG20B
|
high mobility group 20B
|
-5.17103
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-5.00047
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.6393
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-3.90342
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.54525
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.201
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.76465
|
|
GLCE
|
glucuronic acid epimerase
|
-2.6424
|
|
KRT14
|
keratin 14, type I
|
-2.51385
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.3968
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.26515
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.23165
|
|
ILK
|
integrin-linked kinase
|
-2.09705
|
|
DUSP4
|
dual specificity phosphatase 4
|
-2.09693
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
-2.0009
|
