CRCGN015_MCF10A.TP53.M_24H:I11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aroclor 1260 31.94 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCH protein kinase C, eta 5.23318
HLA-DRA major histocompatibility complex, class II, DR alpha 4.50045
CNRIP1 cannabinoid receptor interacting protein 1 4.3923
KIF5C kinesin family member 5C 4.08343
HOXA5 homeobox A5 3.71505
AGR2 anterior gradient 2 3.59605
TSKU tsukushi, small leucine rich proteoglycan 3.44505
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.17585
HBB hemoglobin, beta 3.09557
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.91083
KIF14 kinesin family member 14 2.7563
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.74845
CENPE centromere protein E, 312kDa 2.59295
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.48445
BZW2 basic leucine zipper and W2 domains 2 2.2045
CREG1 cellular repressor of E1A-stimulated genes 1 2.2029
DCP2 decapping mRNA 2 2.10725
TDP1 tyrosyl-DNA phosphodiesterase 1 2.09845
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.08865
SYNGR3 synaptogyrin 3 2.02315

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.90135
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.83385
CD44 CD44 molecule (Indian blood group) -4.57234
KRT14 keratin 14, type I -3.9441
MSMO1 methylsterol monooxygenase 1 -3.05915
CORO1A coronin, actin binding protein, 1A -2.65455
SNX7 sorting nexin 7 -2.60475
CFAP44 cilia and flagella associated protein 44 -2.28905
ATP11B ATPase, class VI, type 11B -2.2192
WDR62 WD repeat domain 62 -2.20825
RUVBL1 RuvB-like AAA ATPase 1 -2.14605
LIN7B lin-7 homolog B (C. elegans) -2.14115
SGK1 serum/glucocorticoid regulated kinase 1 -2.13215
TOR3A torsin family 3, member A -2.1256
CBARP CACN subunit beta associated regulatory protein -2.0886
E4F1 E4F transcription factor 1 -2.0558
NFE2L2 nuclear factor, erythroid 2-like 2 -2.03905
STX4 syntaxin 4 -2.02715
TMEM40 transmembrane protein 40 -2.0216
SYP synaptophysin -2.00775