CRCGN015_MCF10A.TP53.M_24H:I12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aroclor 1260 10.65 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.66275
CHEK1 checkpoint kinase 1 4.6289
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 3.38823
KDM5A lysine (K)-specific demethylase 5A 3.26713
IGFBP3 insulin-like growth factor binding protein 3 2.94753
GSTZ1 glutathione S-transferase zeta 1 2.93815
WASF3 WAS protein family, member 3 2.88845
SATB1 SATB homeobox 1 2.63695
ATRAID all-trans retinoic acid-induced differentiation factor 2.3533
NXPE3 neurexophilin and PC-esterase domain family, member 3 2.2953
NOSIP nitric oxide synthase interacting protein 2.12285
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.1144
PHF10 PHD finger protein 10 2.0709
SHCBP1 SHC SH2-domain binding protein 1 2.05865
PPT1 palmitoyl-protein thioesterase 1 2.04995
CREG1 cellular repressor of E1A-stimulated genes 1 2.0028

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -5.4732
UFM1 ubiquitin-fold modifier 1 -5.1587
MRPS2 mitochondrial ribosomal protein S2 -4.9512
KRT14 keratin 14, type I -3.8844
RALGDS ral guanine nucleotide dissociation stimulator -3.76638
GFUS GDP-L-fucose synthase -3.0922
ATF5 activating transcription factor 5 -2.71645
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.68975
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.28955
PAEP progestagen-associated endometrial protein -2.27775
RPS5 ribosomal protein S5 -2.25345
UBAC1 UBA domain containing 1 -2.24995
KDM3A lysine (K)-specific demethylase 3A -2.2416
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -2.22702
NGRN neugrin, neurite outgrowth associated -2.2083
CRTAP cartilage associated protein -2.04085
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -2.03008