| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | toluene diisocyanate 101.79 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG4 | sperm associated antigen 4 | 5.31135 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 5.0246 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 4.8418 |
| HBA1 | hemoglobin, alpha 1 | 4.75277 |
| KLHL21 | kelch-like family member 21 | 4.688 |
| KDM5D | lysine (K)-specific demethylase 5D | 4.18775 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3.82645 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3.78375 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 3.66293 |
| NGRN | neugrin, neurite outgrowth associated | 3.493 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3.44135 |
| HBB | hemoglobin, beta | 3.39307 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 3.1376 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.58111 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.48348 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.39635 |
| ANGPTL7 | angiopoietin-like 7 | 2.38585 |
| ENDOD1 | endonuclease domain containing 1 | 2.2986 |
| PCDHB11 | protocadherin beta 11 | 2.29756 |
| CETN3 | centrin, EF-hand protein, 3 | 2.2416 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.22525 |
| ZFY | zinc finger protein, Y-linked | 2.2208 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.21965 |
| ZNF106 | zinc finger protein 106 | 2.19535 |
| SRSF8 | serine/arginine-rich splicing factor 8 | 2.16157 |
| SAA2 | serum amyloid A2 | 2.11685 |
| CHUK | conserved helix-loop-helix ubiquitous kinase | 2.08125 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.06455 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.03335 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSPAN4 | tetraspanin 4 | -5.051 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.456 |
| TRAPPC3 | trafficking protein particle complex 3 | -4.2302 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.1939 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.3317 |
| MSN | moesin | -3.2224 |
| SMC1A | structural maintenance of chromosomes 1A | -3.20607 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -3.0474 |
| CLASRP | CLK4-associating serine/arginine rich protein | -2.9804 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -2.9494 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -2.77085 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.63164 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -2.61535 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.42965 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.37485 |
| RBM15B | RNA binding motif protein 15B | -2.3598 |
| PLXND1 | plexin D1 | -2.28225 |
| OFD1 | oral-facial-digital syndrome 1 | -2.25155 |
| ZMYM4 | zinc finger, MYM-type 4 | -2.24053 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.22935 |
| NCBP3 | nuclear cap binding subunit 3 | -2.21845 |
| AGO1 | argonaute RISC catalytic component 1 | -2.21775 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -2.2159 |
| LOC102724594 | splicing factor U2AF 35 kDa subunit | -2.16395 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.1492 |
| TG | thyroglobulin | -2.1429 |
| KDM6A | lysine (K)-specific demethylase 6A | -2.14013 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | -2.0505 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -2.0491 |
| ZNF34 | zinc finger protein 34 | -2.0461 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.04122 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -2.03452 |
| VWF | von Willebrand factor | -2.0264 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -2.02155 |
| EMC6 | ER membrane protein complex subunit 6 | -2.02135 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.0172 |
