| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | toluene diisocyanate 11.31 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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121 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNRIP1 | cannabinoid receptor interacting protein 1 | 6.81135 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.27885 |
| ABHD6 | abhydrolase domain containing 6 | 4.80978 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.68248 |
| ELAVL1 | ELAV like RNA binding protein 1 | 3.60238 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 3.1551 |
| CCNF | cyclin F | 3.10115 |
| DENND2D | DENN/MADD domain containing 2D | 2.9551 |
| CPNE7 | copine VII | 2.9433 |
| TPPP | tubulin polymerization promoting protein | 2.7709 |
| CD248 | CD248 molecule, endosialin | 2.7556 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2.66755 |
| PARN | poly(A)-specific ribonuclease | 2.56685 |
| BMS1 | BMS1 ribosome biogenesis factor | 2.5472 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.48835 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 2.4547 |
| TDRD3 | tudor domain containing 3 | 2.40675 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 2.3984 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | 2.39638 |
| NMI | N-myc (and STAT) interactor | 2.38775 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 2.38535 |
| PLP1 | proteolipid protein 1 | 2.36695 |
| DLL3 | delta-like 3 (Drosophila) | 2.3429 |
| RNF113A | ring finger protein 113A | 2.31625 |
| HOXA10 | homeobox A10 | 2.3022 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 2.30135 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 2.28575 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 2.28337 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 2.2557 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 | 2.22925 |
| DERA | deoxyribose-phosphate aldolase (putative) | 2.20465 |
| NEUROD6 | neuronal differentiation 6 | 2.19 |
| CLTA | clathrin, light chain A | 2.18897 |
| ADRB3 | adrenoceptor beta 3 | 2.1692 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 2.16735 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 2.15 |
| COXFA4 | cytochrome c oxidase associated subunit FA4 | 2.1229 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 2.12005 |
| AGR2 | anterior gradient 2 | 2.1061 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | 2.10313 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 2.0934 |
| NEK9 | NIMA-related kinase 9 | 2.07175 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 2.0642 |
| RPP25 | ribonuclease P/MRP 25kDa subunit | 2.0572 |
| GGNBP2 | gametogenetin binding protein 2 | 2.05615 |
| CDC123 | cell division cycle 123 | 2.05595 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 2.05155 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) | 2.0444 |
| TBCB | tubulin folding cofactor B | 2.04115 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 2.0398 |
| ANXA6 | annexin A6 | 2.03225 |
| NDST4 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 | 2.02645 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 2.0234 |
| SYT1 | synaptotagmin I | 2.02043 |
| ERCC3 | excision repair cross-complementation group 3 | 2.0192 |
| NUP42 | nucleoporin 42 | 2.0131 |
| GDF2 | growth differentiation factor 2 | 2.01135 |
| TSKU | tsukushi, small leucine rich proteoglycan | 2.0089 |
| DSTN | destrin (actin depolymerizing factor) | 2.0033 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLT1B | golgi transport 1B | -5.07795 |
| BID | BH3 interacting domain death agonist | -4.02185 |
| KRT14 | keratin 14, type I | -3.8257 |
| RECQL | RecQ helicase-like | -3.40641 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | -3.3411 |
| MSMO1 | methylsterol monooxygenase 1 | -3.33165 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.1993 |
| WTAP | Wilms tumor 1 associated protein | -2.99395 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -2.97805 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -2.93147 |
| IFRD2 | interferon-related developmental regulator 2 | -2.83332 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.82698 |
| TESK2 | testis-specific kinase 2 | -2.7702 |
| RNF123 | ring finger protein 123 | -2.71035 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.62565 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -2.60798 |
| APEH | acylaminoacyl-peptide hydrolase | -2.5959 |
| TMEM115 | transmembrane protein 115 | -2.59485 |
| JMJD4 | jumonji domain containing 4 | -2.57295 |
| CYB561D2 | cytochrome b561 family, member D2 | -2.5241 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -2.47913 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | -2.4586 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -2.4259 |
| TUSC2 | tumor suppressor candidate 2 | -2.42245 |
| SDC2 | syndecan 2 | -2.41665 |
| NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit | -2.4071 |
| ELOVL4 | ELOVL fatty acid elongase 4 | -2.39735 |
| TLE4 | transducin-like enhancer of split 4 | -2.3875 |
| SOD2 | superoxide dismutase 2, mitochondrial | -2.33628 |
| GMPPB | GDP-mannose pyrophosphorylase B | -2.32005 |
| NCLN | nicalin | -2.31895 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 | -2.316 |
| RMDN3 | regulator of microtubule dynamics 3 | -2.3019 |
| DHCR24 | 24-dehydrocholesterol reductase | -2.28865 |
| REXO2 | RNA exonuclease 2 | -2.28859 |
| ACY1 | aminoacylase 1 | -2.27335 |
| TMEM214 | transmembrane protein 214 | -2.25975 |
| SOAT2 | sterol O-acyltransferase 2 | -2.25253 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -2.2352 |
| TMEM208 | transmembrane protein 208 | -2.22985 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -2.20482 |
| CNPY3-GNMT | CNPY3-GNMT readthrough | -2.19295 |
| SNAI2 | snail family zinc finger 2 | -2.1877 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like | -2.14825 |
| LMF2 | lipase maturation factor 2 | -2.13547 |
| ATG2A | autophagy related 2A | -2.1101 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -2.099 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.07743 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -2.0749 |
| ELMO3 | engulfment and cell motility 3 | -2.0687 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -2.06732 |
| GCAT | glycine C-acetyltransferase | -2.06632 |
| PSKH1 | protein serine kinase H1 | -2.0656 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -2.0644 |
| YIPF3 | Yip1 domain family, member 3 | -2.04975 |
| METTL1 | methyltransferase like 1 | -2.04375 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -2.03875 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -2.0386 |
| TMSB15B | thymosin beta 15B | -2.02575 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | -2.0255 |
| SHFL | shiftless antiviral inhibitor of ribosomal frameshifting | -2.0223 |
| C4BPB | complement component 4 binding protein, beta | -2.0059 |
