CRCGN015_MCF10A.TP53.M_24H:I19 Gene Set
Genes
38 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.84265
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
4.52695
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.51225
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.9104
|
|
B4GAT1
|
beta-1,4-glucuronyltransferase 1
|
3.43995
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
3.16755
|
|
ACLY
|
ATP citrate lyase
|
2.99777
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.53005
|
|
DNM1
|
dynamin 1
|
2.1937
|
|
TMCC2
|
transmembrane and coiled-coil domain family 2
|
2.1802
|
|
RAI14
|
retinoic acid induced 14
|
2.16895
|
|
GRB7
|
growth factor receptor-bound protein 7
|
2.16085
|
|
REG3A
|
regenerating islet-derived 3 alpha
|
2.08735
|
|
ATP8B4
|
ATPase, class I, type 8B, member 4
|
2.07925
|
|
TG
|
thyroglobulin
|
2.0333
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.02455
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.0122
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ANKRD10
|
ankyrin repeat domain 10
|
-6.35355
|
|
KRT14
|
keratin 14, type I
|
-5.52375
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-5.07338
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.9081
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-4.49123
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-4.04805
|
|
SSR4
|
signal sequence receptor, delta
|
-3.3639
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
-2.69565
|
|
TMX2
|
thioredoxin-related transmembrane protein 2
|
-2.64175
|
|
GAS2
|
growth arrest-specific 2
|
-2.4462
|
|
RNF4
|
ring finger protein 4
|
-2.4179
|
|
NAXD
|
NAD(P)HX dehydratase
|
-2.39165
|
|
REXO2
|
RNA exonuclease 2
|
-2.30514
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.2063
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.16665
|
|
IKBKG
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
|
-2.1242
|
|
PRPF3
|
pre-mRNA processing factor 3
|
-2.1057
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.07338
|
|
RPS5
|
ribosomal protein S5
|
-2.065
|
|
CETN2
|
centrin, EF-hand protein, 2
|
-2.04105
|
|
IRAK1
|
interleukin-1 receptor-associated kinase 1
|
-2.02805
|