| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tryptophan 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
94 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 5.1853 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.9417 |
| DENND2D | DENN/MADD domain containing 2D | 4.9057 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.77075 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.73443 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.97797 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.8555 |
| MTA2 | metastasis associated 1 family, member 2 | 3.62505 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.5311 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 3.4452 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.06885 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.9721 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 2.90135 |
| MDM4 | MDM4, p53 regulator | 2.8083 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 2.70103 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.62285 |
| RBBP5 | retinoblastoma binding protein 5 | 2.55405 |
| ATP13A1 | ATPase type 13A1 | 2.54095 |
| CEL | carboxyl ester lipase | 2.49675 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | 2.4849 |
| STATH | statherin | 2.4833 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.46285 |
| NECTIN4 | nectin cell adhesion molecule 4 | 2.39715 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.3898 |
| PLPP6 | phospholipid phosphatase 6 | 2.3843 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 2.37203 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 2.37035 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.36655 |
| HPCAL1 | hippocalcin-like 1 | 2.34183 |
| LPO | lactoperoxidase | 2.2494 |
| CENPE | centromere protein E, 312kDa | 2.2431 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 2.22645 |
| VASP | vasodilator-stimulated phosphoprotein | 2.1997 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 2.1587 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 2.137 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 2.1346 |
| NMU | neuromedin U | 2.1327 |
| RBKS | ribokinase | 2.13 |
| ZNF318 | zinc finger protein 318 | 2.11665 |
| CCNE2 | cyclin E2 | 2.11287 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 2.1117 |
| PYGM | phosphorylase, glycogen, muscle | 2.08855 |
| EBLN2 | endogenous Bornavirus-like nucleoprotein 2 | 2.0644 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 2.0612 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 2.0351 |
| NRTN | neurturin | 2.0324 |
| CNN1 | calponin 1, basic, smooth muscle | 2.0196 |
| FABP6 | fatty acid binding protein 6, ileal | 2.01615 |
| NIBAN1 | niban apoptosis regulator 1 | 2.01548 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRWD1 | glutamate-rich WD repeat containing 1 | -5.91855 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.7623 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.0 |
| HOXA5 | homeobox A5 | -4.4823 |
| HEATR1 | HEAT repeat containing 1 | -4.33418 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -3.77506 |
| TBCE | tubulin folding cofactor E | -3.63713 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.51242 |
| RBM34 | RNA binding motif protein 34 | -3.44017 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -3.2779 |
| COMMD9 | COMM domain containing 9 | -3.1307 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.1094 |
| PRR13 | proline rich 13 | -2.7296 |
| BCAS1 | breast carcinoma amplified sequence 1 | -2.70955 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | -2.6459 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.63453 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -2.51572 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -2.4343 |
| CTSE | cathepsin E | -2.4146 |
| FAM169A | family with sequence similarity 169, member A | -2.41375 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | -2.39625 |
| RPS5 | ribosomal protein S5 | -2.3302 |
| NRN1 | neuritin 1 | -2.2396 |
| SCN1A | sodium channel, voltage gated, type I alpha subunit | -2.2323 |
| TRIP4 | thyroid hormone receptor interactor 4 | -2.2295 |
| ZWILCH | zwilch kinetochore protein | -2.21965 |
| PTK6 | protein tyrosine kinase 6 | -2.21765 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -2.1987 |
| HABP4 | hyaluronan binding protein 4 | -2.16795 |
| NCAM2 | neural cell adhesion molecule 2 | -2.16175 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.15415 |
| EPHA4 | EPH receptor A4 | -2.15215 |
| PCDH17 | protocadherin 17 | -2.1402 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -2.1267 |
| CD81 | CD81 molecule | -2.11065 |
| SKIC3 | SKI3 subunit of superkiller complex | -2.09085 |
| GALT | galactose-1-phosphate uridylyltransferase | -2.07525 |
| COL5A2 | collagen, type V, alpha 2 | -2.0729 |
| TMEM176B | transmembrane protein 176B | -2.0683 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.0405 |
| GMFG | glia maturation factor, gamma | -2.0381 |
| GNPAT | glyceronephosphate O-acyltransferase | -2.03635 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | -2.0214 |
| CD59 | CD59 molecule, complement regulatory protein | -2.02102 |
| EIF6 | eukaryotic translation initiation factor 6 | -2.0083 |
