CRCGN015_MCF10A.TP53.M_24H:J01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hydrazobenzene 101.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

46 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 5.92612
CNRIP1 cannabinoid receptor interacting protein 1 4.7956
CCNA1 cyclin A1 4.26293
COMP cartilage oligomeric matrix protein 4.1546
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.99629
KDM5D lysine (K)-specific demethylase 5D 3.52843
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.46226
SQOR sulfide quinone oxidoreductase 3.44379
GATA2 GATA binding protein 2 3.2424
FGFR4 fibroblast growth factor receptor 4 3.10362
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 3.05319
ACAA1 acetyl-CoA acyltransferase 1 2.88842
HBA1 hemoglobin, alpha 1 2.76042
RNMT RNA (guanine-7-) methyltransferase 2.49086
SEH1L SEH1-like (S. cerevisiae) 2.2638
SMYD2 SET and MYND domain containing 2 2.16437
USP9Y ubiquitin specific peptidase 9, Y-linked 2.11733
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.10475
CHMP1B charged multivesicular body protein 1B 2.09447
OLFML2B olfactomedin-like 2B 2.07275
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.04051

decreased expression

Symbol Name Standardized Value
NGRN neugrin, neurite outgrowth associated -5.4293
NSDHL NAD(P) dependent steroid dehydrogenase-like -4.98994
HMG20B high mobility group 20B -4.36853
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.10714
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.93957
KDM5C lysine (K)-specific demethylase 5C -2.92694
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.64555
KDM6A lysine (K)-specific demethylase 6A -2.57017
KRT14 keratin 14, type I -2.49615
SMC1A structural maintenance of chromosomes 1A -2.38972
UBA1 ubiquitin-like modifier activating enzyme 1 -2.35417
WNT16 wingless-type MMTV integration site family, member 16 -2.31462
MFSD12 major facilitator superfamily domain containing 12 -2.27924
RAD51C RAD51 paralog C -2.27345
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -2.27126
MCAM melanoma cell adhesion molecule -2.26163
USP9X ubiquitin specific peptidase 9, X-linked -2.16664
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -2.16489
MRNIP MRN complex interacting protein -2.13381
TMEM187 transmembrane protein 187 -2.09166
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -2.08991
FAM3A family with sequence similarity 3, member A -2.08272
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.07595
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.05692
BCAP31 B-cell receptor-associated protein 31 -2.03369