CRCGN015_MCF10A.TP53.M_24H:J04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl toluene 99.96 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 4.04366
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.98463
SNAP25 synaptosomal-associated protein, 25kDa 3.37425
BACE2 beta-site APP-cleaving enzyme 2 2.83452
GATA3 GATA binding protein 3 2.61659
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.45586
COMP cartilage oligomeric matrix protein 2.45557
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.40046
ADRB2 adrenoceptor beta 2, surface 2.38529
GARRE1 granule associated Rac and RHOG effector 1 2.35356
LYRM1 LYR motif containing 1 2.29449
JAK1 Janus kinase 1 2.21059
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 2.14731
MRPL34 mitochondrial ribosomal protein L34 2.11108
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.10409
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.08573

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -7.68645
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.28421
TM9SF3 transmembrane 9 superfamily member 3 -3.75528
HMG20B high mobility group 20B -3.72208
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -3.64056
CCNB1 cyclin B1 -3.54638
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.39127
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.22486
SDC1 syndecan 1 -2.53674
GPKOW G patch domain and KOW motifs -2.4817
CCNB2 cyclin B2 -2.47838
ZNF500 zinc finger protein 500 -2.26831
PLA2G12A phospholipase A2, group XIIA -2.18044
NVL nuclear VCP-like -2.17853
IQCB1 IQ motif containing B1 -2.09544
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.03214