CRCGN015_MCF10A.TP53.M_24H:J05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl toluene 33.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TSEN2 TSEN2 tRNA splicing endonuclease subunit 8.54382
ABHD6 abhydrolase domain containing 6 5.32526
BLTP2 bridge-like lipid transfer protein family member 2 3.34164
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 3.13258
MMP1 matrix metallopeptidase 1 3.07893
CDK19 cyclin-dependent kinase 19 2.99606
CCNF cyclin F 2.77122
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.50308
CCL2 chemokine (C-C motif) ligand 2 2.49707
NPR2 natriuretic peptide receptor 2 2.41607
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.28059
TMOD1 tropomodulin 1 2.2075
WNT16 wingless-type MMTV integration site family, member 16 2.08355
RPAP2 RNA polymerase II associated protein 2 2.04506

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -6.08024
TSPAN4 tetraspanin 4 -4.76039
DSG2 desmoglein 2 -4.64233
TXNDC9 thioredoxin domain containing 9 -3.60203
DIPK1A divergent protein kinase domain 1A -3.57373
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.27839
ISOC1 isochorismatase domain containing 1 -3.03837
MSN moesin -2.96135
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.35596
KRT14 keratin 14, type I -2.15379