CRCGN015_MCF10A.TP53.M_24H:J06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl toluene 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

98 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 8.40349
E2F2 E2F transcription factor 2 4.91594
CNRIP1 cannabinoid receptor interacting protein 1 4.78012
SPAG4 sperm associated antigen 4 4.71165
PPARG peroxisome proliferator-activated receptor gamma 4.64086
WFS1 Wolfram syndrome 1 (wolframin) 4.25761
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.84237
RAB31 RAB31, member RAS oncogene family 3.52329
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.07947
CPZ carboxypeptidase Z 3.04408
AGR2 anterior gradient 2 2.83886
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.78861
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.62601
MAN1C1 mannosidase, alpha, class 1C, member 1 2.61979
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.61599
SP3 Sp3 transcription factor 2.58556
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.57961
TCF21 transcription factor 21 2.55607
RPS11 ribosomal protein S11 2.55587
AGER advanced glycosylation end product-specific receptor 2.55475
TBC1D2 TBC1 domain family, member 2 2.54742
ZNF556 zinc finger protein 556 2.52073
PCSK5 proprotein convertase subtilisin/kexin type 5 2.51995
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 2.51265
ZBTB32 zinc finger and BTB domain containing 32 2.43385
RPL38 ribosomal protein L38 2.42632
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 2.40022
PLAC8 placenta-specific 8 2.38276
GSTZ1 glutathione S-transferase zeta 1 2.35652
PROX1 prospero homeobox 1 2.27965
TJP2 tight junction protein 2 2.27942
TNXB tenascin XB 2.27294
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.19455
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 2.19036
MELTF melanotransferrin 2.15529
GRAP2 GRB2-related adaptor protein 2 2.15323
KIAA0040 KIAA0040 2.14148
HNRNPF heterogeneous nuclear ribonucleoprotein F 2.13357
GSTM5 glutathione S-transferase mu 5 2.12945
TMEM101 transmembrane protein 101 2.12169
TCEAL1 transcription elongation factor A (SII)-like 1 2.11089
CERS1 ceramide synthase 1 2.10782
DIO2 deiodinase, iodothyronine, type II 2.09978
SSX3 synovial sarcoma, X breakpoint 3 2.09794
STXBP3 syntaxin binding protein 3 2.09151
PLIN3 perilipin 3 2.08804
RPL34 ribosomal protein L34 2.08522
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.07244
PELI2 pellino E3 ubiquitin protein ligase family member 2 2.07114
MMP24-AS1-EDEM2 MMP24-AS1-EDEM2 readthrough 2.06985
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 2.06927
HOXD10 homeobox D10 2.06045
ZNF189 zinc finger protein 189 2.05569
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.05534
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.04938
LAMC3 laminin, gamma 3 2.04139
CD101 CD101 molecule 2.04101
ENO3 enolase 3 (beta, muscle) 2.0407
MROH7 maestro heat-like repeat family member 7 2.03419
RFX2 regulatory factor X, 2 (influences HLA class II expression) 2.02774
RPH3AL rabphilin 3A-like (without C2 domains) 2.0269
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.02561
RPGR retinitis pigmentosa GTPase regulator 2.02506
RBL1 retinoblastoma-like 1 2.02463
MMP26 matrix metallopeptidase 26 2.0207
H2BC11 H2B clustered histone 11 2.01972
ACSBG2 acyl-CoA synthetase bubblegum family member 2 2.01478
TBC1D31 TBC1 domain family, member 31 2.0109
CD300C CD300c molecule 2.00956
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 2.00898
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.00727
RPL27 ribosomal protein L27 2.00495
PDE3B phosphodiesterase 3B, cGMP-inhibited 2.00453
RPL8 ribosomal protein L8 2.00291
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.0025

decreased expression

Symbol Name Standardized Value
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.97058
CD81 CD81 molecule -4.91768
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.79321
JMJD6 jumonji domain containing 6 -3.88536
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -3.09393
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -2.97579
LUC7L LUC7-like (S. cerevisiae) -2.50711
CREB3L4 cAMP responsive element binding protein 3-like 4 -2.49083
ATG101 autophagy related 101 -2.4495
H1-0 H1.0 linker histone -2.44892
IFRD2 interferon-related developmental regulator 2 -2.40571
TENT4A terminal nucleotidyltransferase 4A -2.31475
PTS 6-pyruvoyltetrahydropterin synthase -2.30859
UNKL unkempt family zinc finger-like -2.30211
AUTS2 autism susceptibility candidate 2 -2.25366
BTG3 BTG family, member 3 -2.23316
RHOT2 ras homolog family member T2 -2.18441
TBC1D16 TBC1 domain family, member 16 -2.18105
NR4A2 nuclear receptor subfamily 4, group A, member 2 -2.15431
APEH acylaminoacyl-peptide hydrolase -2.12859
NGF nerve growth factor (beta polypeptide) -2.09786
ZNF281 zinc finger protein 281 -2.06236
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.02669