CRCGN015_MCF10A.TP53.M_24H:J14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethylamine 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 10.0
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.73015
HBA1 hemoglobin, alpha 1 4.44177
HBB hemoglobin, beta 3.98227
ACAA1 acetyl-CoA acyltransferase 1 3.38033
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.9491
MINDY1 MINDY lysine 48 deubiquitinase 1 2.6407
STAMBP STAM binding protein 2.4255
TLCD3A TLC domain containing 3A 2.272
RXYLT1 ribitol xylosyltransferase 1 2.07492
TENT5C terminal nucleotidyltransferase 5C 2.0491
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.04045
DEFA3 defensin, alpha 3, neutrophil-specific 2.01995

decreased expression

Symbol Name Standardized Value
SMNDC1 survival motor neuron domain containing 1 -5.49925
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.76855
CD44 CD44 molecule (Indian blood group) -4.35025
WASHC4 WASH complex subunit 4 -4.10412
CD81 CD81 molecule -4.0923
SGK1 serum/glucocorticoid regulated kinase 1 -3.3931
NT5DC2 5'-nucleotidase domain containing 2 -2.9582
STK25 serine/threonine kinase 25 -2.49115
NT5DC3 5'-nucleotidase domain containing 3 -2.4049
KRT14 keratin 14, type I -2.35635
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -2.30105
CAPN10 calpain 10 -2.1561