CRCGN015_MCF10A.TP53.M_24H:J15 Gene Set
Genes
50 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
5.07535
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
5.0
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.95745
|
|
CLNS1A
|
chloride channel, nucleotide-sensitive, 1A
|
4.2376
|
|
WIF1
|
WNT inhibitory factor 1
|
3.8037
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.68375
|
|
EMSY
|
EMSY transcriptional repressor, BRCA2 interacting
|
3.2203
|
|
HBA1
|
hemoglobin, alpha 1
|
3.07454
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
3.01815
|
|
NARS2
|
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
|
2.90905
|
|
PKN1
|
protein kinase N1
|
2.70553
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.61217
|
|
AAMDC
|
adipogenesis associated, Mth938 domain containing
|
2.54665
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.46347
|
|
RSF1
|
remodeling and spacing factor 1
|
2.4291
|
|
ALG8
|
ALG8, alpha-1,3-glucosyltransferase
|
2.3691
|
|
HBB
|
hemoglobin, beta
|
2.35075
|
|
DNM2
|
dynamin 2
|
2.3325
|
|
RFX5
|
regulatory factor X, 5 (influences HLA class II expression)
|
2.26145
|
|
THAP12
|
THAP domain containing 12
|
2.24175
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
2.2293
|
|
CETN3
|
centrin, EF-hand protein, 3
|
2.22025
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.1787
|
|
ZNF266
|
zinc finger protein 266
|
2.123
|
|
EED
|
embryonic ectoderm development
|
2.10317
|
|
RANGRF
|
RAN guanine nucleotide release factor
|
2.0951
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.0359
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB1
|
cyclin B1
|
-5.3023
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-4.98303
|
|
TEX10
|
testis expressed 10
|
-4.97975
|
|
PMM2
|
phosphomannomutase 2
|
-4.90885
|
|
TCTA
|
T-cell leukemia translocation altered
|
-4.90255
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.36967
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.1006
|
|
CAB39
|
calcium binding protein 39
|
-3.41015
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.6464
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.63635
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.43215
|
|
CNNM3
|
cyclin and CBS domain divalent metal cation transport mediator 3
|
-2.3302
|
|
CHPF
|
chondroitin polymerizing factor
|
-2.32265
|
|
STARD7
|
StAR-related lipid transfer (START) domain containing 7
|
-2.22505
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.20095
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.182
|
|
IMP4
|
IMP4, U3 small nucleolar ribonucleoprotein
|
-2.1815
|
|
RABGGTA
|
Rab geranylgeranyltransferase, alpha subunit
|
-2.1699
|
|
MKLN1
|
muskelin 1, intracellular mediator containing kelch motifs
|
-2.1376
|
|
IL6
|
interleukin 6
|
-2.09645
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
-2.05537
|
|
REV1
|
REV1, polymerase (DNA directed)
|
-2.037
|
|
ACVR2A
|
activin A receptor, type IIA
|
-2.0009
|
