| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(1-naphthyl)ethylenediamine.2hcl 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.79572 |
| GATA3 | GATA binding protein 3 | 4.06775 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.68788 |
| STMN2 | stathmin 2 | 3.5085 |
| TCEA2 | transcription elongation factor A (SII), 2 | 3.3128 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 3.12665 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.0511 |
| MMP1 | matrix metallopeptidase 1 | 2.80058 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 2.7944 |
| SYT1 | synaptotagmin I | 2.65668 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.53045 |
| TSKU | tsukushi, small leucine rich proteoglycan | 2.4897 |
| CHN1 | chimerin 1 | 2.3223 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 2.3093 |
| COL4A5 | collagen, type IV, alpha 5 | 2.2742 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.2482 |
| PMCH | pro-melanin-concentrating hormone | 2.20995 |
| TAC1 | tachykinin, precursor 1 | 2.18945 |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 2.1856 |
| SQOR | sulfide quinone oxidoreductase | 2.1838 |
| CEP15 | centrosomal protein 15 | 2.1669 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 2.14768 |
| MFAP4 | microfibrillar-associated protein 4 | 2.13095 |
| EPHA3 | EPH receptor A3 | 2.11825 |
| S100A4 | S100 calcium binding protein A4 | 2.11655 |
| TAGLN3 | transgelin 3 | 2.1062 |
| METTL25B | methyltransferase like 25B | 2.0736 |
| SFRP5 | secreted frizzled-related protein 5 | 2.0681 |
| BCAP31 | B-cell receptor-associated protein 31 | 2.06165 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) | 2.06155 |
| RUNDC3A | RUN domain containing 3A | 2.05505 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 2.0139 |
| IP6K1 | inositol hexakisphosphate kinase 1 | 2.00135 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPIA | ribose 5-phosphate isomerase A | -5.67255 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -5.34355 |
| DCK | deoxycytidine kinase | -5.16955 |
| PCNA | proliferating cell nuclear antigen | -5.0 |
| COTL1 | coactosin-like F-actin binding protein 1 | -4.26265 |
| PFN1 | profilin 1 | -3.8915 |
| THAP11 | THAP domain containing 11 | -3.40965 |
| CD320 | CD320 molecule | -3.2043 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.1039 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.84629 |
| C1QBP | complement component 1, q subcomponent binding protein | -2.78492 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.7263 |
| RAD51C | RAD51 paralog C | -2.7126 |
| PANK2 | pantothenate kinase 2 | -2.64605 |
| ADRB2 | adrenoceptor beta 2, surface | -2.5965 |
| HSPA1A | heat shock 70kDa protein 1A | -2.5939 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.49807 |
| FBXO7 | F-box protein 7 | -2.4784 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.36605 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -2.35715 |
| LOC112694756 | uncharaterized LOC112694756 | -2.32342 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.3068 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.2524 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.22213 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -2.2183 |
| ZMAT3 | zinc finger, matrin-type 3 | -2.175 |
| ITGB5 | integrin, beta 5 | -2.15527 |
| TMEM9B | TMEM9 domain family, member B | -2.11925 |
| PRR5L | proline rich 5 like | -2.0964 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -2.0951 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -2.08405 |
| LDHA | lactate dehydrogenase A | -2.07795 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.0706 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -2.06985 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | -2.06365 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.04725 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -2.0045 |
