CRCGN015_MCF10A.TP53.M_24H:J18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-(1-naphthyl)ethylenediamine.2hcl 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 5.1997
PPARG peroxisome proliferator-activated receptor gamma 4.762
CCL2 chemokine (C-C motif) ligand 2 4.43715
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.7063
FCHO1 FCH domain only 1 2.17665
CCDC85B coiled-coil domain containing 85B 2.0747

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.97965
HMG20B high mobility group 20B -4.80247
PSIP1 PC4 and SFRS1 interacting protein 1 -3.58625
ANKRD10 ankyrin repeat domain 10 -3.5023
HSPA1A heat shock 70kDa protein 1A -2.35435
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.26188
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.1811
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.04385