| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dichlorophenol 33.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | 4.31531 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 4.25804 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 3.66268 |
| SPAG4 | sperm associated antigen 4 | 3.56583 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.52259 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.4115 |
| CCDC92 | coiled-coil domain containing 92 | 3.18315 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.15378 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 3.03081 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 2.69124 |
| FGFR4 | fibroblast growth factor receptor 4 | 2.61827 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.57953 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.55755 |
| THBD | thrombomodulin | 2.42147 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.37861 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.26126 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.22604 |
| ESRP2 | epithelial splicing regulatory protein 2 | 2.1906 |
| SLN | sarcolipin | 2.16965 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 2.15945 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 2.11019 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.09682 |
| ANKRD49 | ankyrin repeat domain 49 | 2.09369 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.08137 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 | 2.00576 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ISOC1 | isochorismatase domain containing 1 | -4.33791 |
| HMG20B | high mobility group 20B | -3.73103 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.72495 |
| KRT14 | keratin 14, type I | -3.71528 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -3.55537 |
| ATG3 | autophagy related 3 | -3.53245 |
| LAP3 | leucine aminopeptidase 3 | -3.51266 |
| TES | testin LIM domain protein | -3.46208 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.36388 |
| RNF167 | ring finger protein 167 | -3.19292 |
| MSMO1 | methylsterol monooxygenase 1 | -3.18083 |
| COG2 | component of oligomeric golgi complex 2 | -3.11965 |
| RPIA | ribose 5-phosphate isomerase A | -3.0817 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -3.05964 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.85003 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.74925 |
| RPS5 | ribosomal protein S5 | -2.63166 |
| CD320 | CD320 molecule | -2.44924 |
| PAEP | progestagen-associated endometrial protein | -2.40558 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | -2.37719 |
| SCRIB | scribbled planar cell polarity protein | -2.36141 |
| ZC3H3 | zinc finger CCCH-type containing 3 | -2.23448 |
| EXO1 | exonuclease 1 | -2.21408 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.12986 |
| MTA1 | metastasis associated 1 | -2.08489 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -2.0671 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -2.03333 |
