CRCGN015_MCF10A.TP53.M_24H:K03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenol 11.03 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

27 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 3.94451
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 3.67122
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.56099
AMDHD2 amidohydrolase domain containing 2 3.4278
CCDC92 coiled-coil domain containing 92 3.16465
ESRP2 epithelial splicing regulatory protein 2 2.94243
COMP cartilage oligomeric matrix protein 2.83296
HBB hemoglobin, beta 2.69447
CNRIP1 cannabinoid receptor interacting protein 1 2.5962
SMIM40 small integral membrane protein 40 2.17749
CCL2 chemokine (C-C motif) ligand 2 2.15999
CHN1 chimerin 1 2.06177
FBXL12 F-box and leucine-rich repeat protein 12 2.05772

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -4.15454
RNF167 ring finger protein 167 -3.87016
COTL1 coactosin-like F-actin binding protein 1 -3.82794
OXA1L oxidase (cytochrome c) assembly 1-like -3.80067
SLC25A46 solute carrier family 25, member 46 -3.17329
HAT1 histone acetyltransferase 1 -3.16006
GNAS GNAS complex locus -2.73064
SORBS3 sorbin and SH3 domain containing 3 -2.59893
STK25 serine/threonine kinase 25 -2.25328
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.18875
SGK1 serum/glucocorticoid regulated kinase 1 -2.18522
THAP11 THAP domain containing 11 -2.05088
GPR52 G protein-coupled receptor 52 -2.03236
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -2.00482