| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethoxane 98.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 6.219 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 5.7048 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 5.61735 |
| TRAP1 | TNF receptor-associated protein 1 | 5.316 |
| TBX2 | T-box 2 | 3.45902 |
| STAMBP | STAM binding protein | 3.31805 |
| NOSIP | nitric oxide synthase interacting protein | 3.01685 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.9809 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 2.97665 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.95265 |
| CCNA1 | cyclin A1 | 2.903 |
| LGALSL | lectin, galactoside-binding-like | 2.7382 |
| PHF21A | PHD finger protein 21A | 2.71445 |
| TMEM135 | transmembrane protein 135 | 2.6706 |
| CHN1 | chimerin 1 | 2.5991 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 2.3214 |
| LTA4H | leukotriene A4 hydrolase | 2.3139 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 2.2819 |
| INAVA | innate immunity activator | 2.2066 |
| IGSF3 | immunoglobulin superfamily, member 3 | 2.19935 |
| ACBD3 | acyl-CoA binding domain containing 3 | 2.1724 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 2.1637 |
| KDM5B | lysine (K)-specific demethylase 5B | 2.13855 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.1306 |
| TRIM39-RPP21 | TRIM39-RPP21 readthrough | 2.09725 |
| WDR83OS | WD repeat domain 83 opposite strand | 2.0949 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 2.0936 |
| EVL | Enah/Vasp-like | 2.09215 |
| DGUOK | deoxyguanosine kinase | 2.09188 |
| ANKRD17 | ankyrin repeat domain 17 | 2.0868 |
| FAT2 | FAT atypical cadherin 2 | 2.06725 |
| RAB38 | RAB38, member RAS oncogene family | 2.0532 |
| FOCAD | focadhesin | 2.0183 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRWD1 | glutamate-rich WD repeat containing 1 | -6.3903 |
| RNF167 | ring finger protein 167 | -5.20005 |
| ATF5 | activating transcription factor 5 | -4.97838 |
| CCNB1 | cyclin B1 | -4.89075 |
| UFM1 | ubiquitin-fold modifier 1 | -4.88875 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -4.8549 |
| CD44 | CD44 molecule (Indian blood group) | -4.15126 |
| C1QBP | complement component 1, q subcomponent binding protein | -3.93567 |
| FPGS | folylpolyglutamate synthase | -3.03635 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -2.9237 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -2.82802 |
| NUP88 | nucleoporin 88kDa | -2.82197 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.81222 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.77365 |
| PFN1 | profilin 1 | -2.7297 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.65688 |
| THAP11 | THAP domain containing 11 | -2.49245 |
| CBR3 | carbonyl reductase 3 | -2.43645 |
| DTWD1 | DTW domain containing 1 | -2.4117 |
| ZNF574 | zinc finger protein 574 | -2.3729 |
| ELAC2 | elaC ribonuclease Z 2 | -2.3077 |
| MIS12 | MIS12 kinetochore complex component | -2.30455 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.2638 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.25295 |
| LOXL1 | lysyl oxidase-like 1 | -2.15905 |
| CRTAP | cartilage associated protein | -2.1578 |
| ARSJ | arylsulfatase family, member J | -2.1116 |
| SERPINA4 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 | -2.0986 |
| CISH | cytokine inducible SH2-containing protein | -2.066 |
| ZNF646 | zinc finger protein 646 | -2.06455 |
| BAALC | brain and acute leukemia, cytoplasmic | -2.06185 |
| RAB23 | RAB23, member RAS oncogene family | -2.0606 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | -2.03845 |
| CH25H | cholesterol 25-hydroxylase | -2.0211 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | -2.02022 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -2.01845 |
| FASN | fatty acid synthase | -2.00551 |
| APOL6 | apolipoprotein L, 6 | -2.005 |
