CRCGN015_MCF10A.TP53.M_24H:K05 Gene Set
Genes
36 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.61134
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
4.50329
|
|
PDLIM1
|
PDZ and LIM domain 1
|
4.12425
|
|
POLD4
|
polymerase (DNA-directed), delta 4, accessory subunit
|
3.97937
|
|
SNX11
|
sorting nexin 11
|
3.4971
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.49403
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
3.45341
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.36258
|
|
PRKCD
|
protein kinase C, delta
|
3.27693
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.10881
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
2.80799
|
|
BAX
|
BCL2-associated X protein
|
2.51656
|
|
HBA1
|
hemoglobin, alpha 1
|
2.5026
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
2.32026
|
|
EBI3
|
Epstein-Barr virus induced 3
|
2.28081
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.27299
|
|
EDN1
|
endothelin 1
|
2.21172
|
|
POLR1D
|
polymerase (RNA) I polypeptide D, 16kDa
|
2.15572
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.00538
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
RPIA
|
ribose 5-phosphate isomerase A
|
-4.64951
|
|
RNF167
|
ring finger protein 167
|
-4.21665
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-4.06999
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-3.99661
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.80139
|
|
HAT1
|
histone acetyltransferase 1
|
-3.46438
|
|
SLC25A46
|
solute carrier family 25, member 46
|
-3.43528
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.42627
|
|
MRPS15
|
mitochondrial ribosomal protein S15
|
-3.12957
|
|
LYPLA1
|
lysophospholipase I
|
-2.77
|
|
CD58
|
CD58 molecule
|
-2.36783
|
|
SLC12A7
|
solute carrier family 12 (potassium/chloride transporter), member 7
|
-2.29672
|
|
KRT14
|
keratin 14, type I
|
-2.23864
|
|
IL4R
|
interleukin 4 receptor
|
-2.18429
|
|
BLCAP
|
bladder cancer associated protein
|
-2.18121
|
|
ERBIN
|
erbb2 interacting protein
|
-2.03221
|
|
DUSP4
|
dual specificity phosphatase 4
|
-2.00884
|
