| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethoxane 10.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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101 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | 5.23833 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 5.10622 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.06133 |
| ABHD4 | abhydrolase domain containing 4 | 4.99369 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 4.99064 |
| INTS3 | integrator complex subunit 3 | 4.84451 |
| AGR2 | anterior gradient 2 | 4.75186 |
| ANO10 | anoctamin 10 | 4.70503 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 4.49336 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.40065 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.36905 |
| TLR4 | toll-like receptor 4 | 3.74172 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.62323 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 3.53069 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 3.43637 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.28295 |
| NES | nestin | 2.83348 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 2.69569 |
| BIN3 | bridging integrator 3 | 2.69018 |
| SIRT3 | sirtuin 3 | 2.63256 |
| PKN1 | protein kinase N1 | 2.62316 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 2.56624 |
| DAD1 | defender against cell death 1 | 2.56259 |
| BMAL1 | basic helix-loop-helix ARNT like 1 | 2.48592 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 2.40366 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 2.3695 |
| ARC | activity-regulated cytoskeleton-associated protein | 2.31659 |
| NPY1R | neuropeptide Y receptor Y1 | 2.30993 |
| DSTN | destrin (actin depolymerizing factor) | 2.28524 |
| SIRT1 | sirtuin 1 | 2.25724 |
| TUBA1B | tubulin, alpha 1b | 2.22967 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 2.22796 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.21095 |
| KIF3C | kinesin family member 3C | 2.20394 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | 2.20242 |
| MRPL23 | mitochondrial ribosomal protein L23 | 2.19893 |
| RBMX2 | RNA binding motif protein, X-linked 2 | 2.19373 |
| RSF1 | remodeling and spacing factor 1 | 2.16866 |
| PLSCR3 | phospholipid scramblase 3 | 2.16107 |
| GPM6B | glycoprotein M6B | 2.15654 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase | 2.14594 |
| STK26 | serine/threonine protein kinase 26 | 2.13846 |
| TUBA1C | tubulin, alpha 1c | 2.09688 |
| CXXC1 | CXXC finger protein 1 | 2.09375 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) | 2.08018 |
| LYRM9 | LYR motif containing 9 | 2.07691 |
| RPS26 | ribosomal protein S26 | 2.06768 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 | 2.06157 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 2.05082 |
| CDX2 | caudal type homeobox 2 | 2.02345 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 2.01453 |
| STX8 | syntaxin 8 | 2.00738 |
| MORF4L2 | mortality factor 4 like 2 | 2.00588 |
| JADE1 | jade family PHD finger 1 | 2.00563 |
| PROSER1 | proline and serine rich 1 | 2.00428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF20A | kinesin family member 20A | -4.69233 |
| CCNB2 | cyclin B2 | -4.62407 |
| DIPK1A | divergent protein kinase domain 1A | -4.36545 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.31243 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.98136 |
| PRPF4 | pre-mRNA processing factor 4 | -3.53737 |
| TENT4A | terminal nucleotidyltransferase 4A | -3.26261 |
| RMDN3 | regulator of microtubule dynamics 3 | -3.22602 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -3.01379 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -2.90122 |
| ACY1 | aminoacylase 1 | -2.73884 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | -2.59595 |
| IFRD2 | interferon-related developmental regulator 2 | -2.59346 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -2.58598 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -2.54098 |
| ZBED2 | zinc finger, BED-type containing 2 | -2.50201 |
| APEH | acylaminoacyl-peptide hydrolase | -2.49808 |
| FBXO21 | F-box protein 21 | -2.44912 |
| S100A1 | S100 calcium binding protein A1 | -2.34254 |
| KRT23 | keratin 23, type I | -2.32366 |
| SFMBT1 | Scm-like with four mbt domains 1 | -2.29886 |
| DHX30 | DEAH (Asp-Glu-Ala-His) box helicase 30 | -2.28067 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | -2.26992 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.26307 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -2.24255 |
| EMC7 | ER membrane protein complex subunit 7 | -2.23312 |
| EPYC | epiphycan | -2.22353 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -2.2099 |
| SLAMF8 | SLAM family member 8 | -2.16178 |
| FZD10 | frizzled class receptor 10 | -2.16 |
| TMPRSS3 | transmembrane protease, serine 3 | -2.14986 |
| KAT2A | K(lysine) acetyltransferase 2A | -2.14156 |
| DES | desmin | -2.13689 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | -2.12113 |
| TOR1B | torsin family 1, member B (torsin B) | -2.10527 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 | -2.09826 |
| PDCD6 | programmed cell death 6 | -2.08766 |
| SPATA5L1 | spermatogenesis associated 5-like 1 | -2.08755 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | -2.07965 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | -2.07352 |
| GJB1 | gap junction protein, beta 1, 32kDa | -2.05 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 | -2.04557 |
| RNF123 | ring finger protein 123 | -2.04305 |
| DUSP14 | dual specificity phosphatase 14 | -2.01066 |
| NMU | neuromedin U | -2.00954 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -2.00002 |
