CRCGN015_MCF10A.TP53.M_24H:K14 Gene Set
Genes
31 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
7.09608
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
5.07015
|
|
KLHL21
|
kelch-like family member 21
|
4.7637
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.75355
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
3.14925
|
|
AGR2
|
anterior gradient 2
|
2.78835
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.7578
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.6456
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.5204
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.4384
|
|
WWC2
|
WW and C2 domain containing 2
|
2.3223
|
|
ECSIT
|
ECSIT signalling integrator
|
2.2716
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
2.239
|
|
USP6
|
ubiquitin specific peptidase 6
|
2.21285
|
|
MED24
|
mediator complex subunit 24
|
2.02745
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.0271
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.91215
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-4.16038
|
|
TCTA
|
T-cell leukemia translocation altered
|
-4.1572
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.97172
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-3.93105
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-3.8003
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.0893
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.9569
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.6771
|
|
SSH1
|
slingshot protein phosphatase 1
|
-2.3753
|
|
STK25
|
serine/threonine kinase 25
|
-2.06215
|
|
DECR1
|
2,4-dienoyl CoA reductase 1, mitochondrial
|
-2.0421
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.03355
|
|
SIN3B
|
SIN3 transcription regulator family member B
|
-2.02778
|
|
HSD17B2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
-2.011
|
