CRCGN015_MCF10A.TP53.M_24H:K16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyraldehyde 101.79 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 3.79545
MCUR1 mitochondrial calcium uniporter regulator 1 3.04885
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.872
HBA1 hemoglobin, alpha 1 2.67243
CYREN cell cycle regulator of NHEJ 2.41605
HJURP Holliday junction recognition protein 2.4032
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.1933
CREG1 cellular repressor of E1A-stimulated genes 1 2.0725
GSTK1 glutathione S-transferase kappa 1 2.05045
OLFML2B olfactomedin-like 2B 2.02425

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -7.6606
NPDC1 neural proliferation, differentiation and control, 1 -5.4877
CHIC2 cysteine-rich hydrophobic domain 2 -5.33725
BASP1 brain abundant, membrane attached signal protein 1 -5.01505
TRAPPC3 trafficking protein particle complex 3 -4.3243
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -3.35105
HSPA1A heat shock 70kDa protein 1A -3.35105
VDAC1 voltage-dependent anion channel 1 -3.30683
BCOR BCL6 corepressor -2.72075
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.71415
MRPS15 mitochondrial ribosomal protein S15 -2.27025
IL4R interleukin 4 receptor -2.26115
NAV2 neuron navigator 2 -2.2482
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.2294
COTL1 coactosin-like F-actin binding protein 1 -2.21205
ANKRD36C ankyrin repeat domain 36C -2.1708
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.1597
HLA-F major histocompatibility complex, class I, F -2.08903
MUC13 mucin 13, cell surface associated -2.01755