| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | isobutyraldehyde 33.93 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.95666 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.6268 |
| WDR7 | WD repeat domain 7 | 4.5393 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 3.92255 |
| HBA1 | hemoglobin, alpha 1 | 3.79418 |
| SNX11 | sorting nexin 11 | 3.63865 |
| RAB31 | RAB31, member RAS oncogene family | 3.5481 |
| GPC1 | glypican 1 | 3.23387 |
| MTA2 | metastasis associated 1 family, member 2 | 3.1313 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.8657 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.77707 |
| RBBP5 | retinoblastoma binding protein 5 | 2.6888 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 2.67295 |
| MDM4 | MDM4, p53 regulator | 2.6672 |
| SATB1 | SATB homeobox 1 | 2.61265 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.47295 |
| DENND2D | DENN/MADD domain containing 2D | 2.42365 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 | 2.35182 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.28875 |
| TBPL1 | TBP-like 1 | 2.27285 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.2307 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 2.18075 |
| EPN3 | epsin 3 | 2.1681 |
| SPRING1 | SREBF pathway regulator in golgi 1 | 2.11835 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 2.1101 |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 2.0777 |
| IL22RA1 | interleukin 22 receptor, alpha 1 | 2.066 |
| GRHL2 | grainyhead-like 2 (Drosophila) | 2.0461 |
| TPD52L2 | tumor protein D52-like 2 | 2.03745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PARP2 | poly (ADP-ribose) polymerase 2 | -6.00522 |
| HMG20B | high mobility group 20B | -4.65468 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.32965 |
| KRT14 | keratin 14, type I | -3.79065 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.24878 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.09305 |
| THAP11 | THAP domain containing 11 | -2.91735 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.7433 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -2.65852 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.60175 |
| DUSP4 | dual specificity phosphatase 4 | -2.5369 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.5236 |
| OSGEP | O-sialoglycoprotein endopeptidase | -2.4217 |
| METTL3 | methyltransferase like 3 | -2.4164 |
| DAZAP1 | DAZ associated protein 1 | -2.33085 |
| TRIB3 | tribbles pseudokinase 3 | -2.29225 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -2.1154 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -2.0763 |
| GMFB | glia maturation factor, beta | -2.05043 |
| SLC2A14 | solute carrier family 2 (facilitated glucose transporter), member 14 | -2.04918 |
| METTL17 | methyltransferase like 17 | -2.0361 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -2.03265 |
| BRD7 | bromodomain containing 7 | -2.0297 |
