CRCGN015_MCF10A.TP53.M_24H:K19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description kynurenic-acid 103.62 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 10.0
CCP110 centriolar coiled coil protein 110kDa 4.90675
NISCH nischarin 4.76455
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.7913
HBA1 hemoglobin, alpha 1 3.75467
DENND2D DENN/MADD domain containing 2D 3.17225
VGLL4 vestigial-like family member 4 2.98977
STK10 serine/threonine kinase 10 2.67565
DDR1 discoidin domain receptor tyrosine kinase 1 2.60495
CAPN7 calpain 7 2.35407
HBB hemoglobin, beta 2.32093
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.31353
LTF lactotransferrin 2.24705
MMP1 matrix metallopeptidase 1 2.23797

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -5.13165
PMM2 phosphomannomutase 2 -4.9648
CCNB1 cyclin B1 -4.6182
CD44 CD44 molecule (Indian blood group) -4.49032
GADD45B growth arrest and DNA-damage-inducible, beta -4.19508
ATF5 activating transcription factor 5 -4.00693
SGK1 serum/glucocorticoid regulated kinase 1 -3.7979
RGS2 regulator of G-protein signaling 2 -2.9613
ATP11B ATPase, class VI, type 11B -2.8016
ZNF551 zinc finger protein 551 -2.1387
DPP6 dipeptidyl-peptidase 6 -2.05155
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.01265