| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | kynurenic-acid 11.51 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FKBP14 | FK506 binding protein 14, 22 kDa | 4.76495 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 4.56547 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 4.35735 |
| LGMN | legumain | 3.5817 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 3.5148 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 3.05715 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.0404 |
| TBC1D31 | TBC1 domain family, member 31 | 2.98615 |
| DENND2D | DENN/MADD domain containing 2D | 2.94 |
| ADRB2 | adrenoceptor beta 2, surface | 2.56995 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.4511 |
| METTL4 | methyltransferase like 4 | 2.23825 |
| GTPBP8 | GTP-binding protein 8 (putative) | 2.1823 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 2.17623 |
| LOC102723713 | TP53-target gene 3 protein | 2.1445 |
| SCAND1 | SCAN domain containing 1 | 2.06265 |
| ZNF76 | zinc finger protein 76 | 2.06225 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 2.0556 |
| PLXDC1 | plexin domain containing 1 | 2.04533 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 2.0436 |
| TRAPPC6A | trafficking protein particle complex 6A | 2.04065 |
| CSNK1A1 | casein kinase 1, alpha 1 | 2.0274 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 2.02405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -5.08273 |
| HMG20B | high mobility group 20B | -4.14653 |
| CD320 | CD320 molecule | -3.7527 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.1355 |
| RBM34 | RNA binding motif protein 34 | -3.03042 |
| SSR4 | signal sequence receptor, delta | -2.9883 |
| TUBA4A | tubulin, alpha 4a | -2.9579 |
| CORO1A | coronin, actin binding protein, 1A | -2.7759 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.7202 |
| YY1AP1 | YY1 associated protein 1 | -2.67915 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.6469 |
| CETN2 | centrin, EF-hand protein, 2 | -2.6461 |
| KRT14 | keratin 14, type I | -2.6157 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -2.59375 |
| ILK | integrin-linked kinase | -2.5469 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | -2.4393 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | -2.43077 |
| BCAP31 | B-cell receptor-associated protein 31 | -2.33945 |
| VBP1 | von Hippel-Lindau binding protein 1 | -2.2898 |
| FAM50A | family with sequence similarity 50, member A | -2.2893 |
| NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit | -2.26405 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.24145 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma | -2.174 |
| MTM1 | myotubularin 1 | -2.1712 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -2.1225 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -2.11445 |
| RHOF | ras homolog family member F (in filopodia) | -2.0801 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -2.06335 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | -2.0444 |
| SDC4 | syndecan 4 | -2.0336 |
| MSMO1 | methylsterol monooxygenase 1 | -2.01675 |
