CRCGN015_MCF10A.TP53.M_24H:K23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(2-chloroethyl) phosphate 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.2375
SNAP25 synaptosomal-associated protein, 25kDa 4.9079
SPAG4 sperm associated antigen 4 4.90755
GHR growth hormone receptor 3.49315
STMN2 stathmin 2 3.0544
WIF1 WNT inhibitory factor 1 2.9363
SYT1 synaptotagmin I 2.61
TAGLN3 transgelin 3 2.5498
PECR peroxisomal trans-2-enoyl-CoA reductase 2.5371
SV2B synaptic vesicle glycoprotein 2B 2.501
NSG2 neuronal vesicle trafficking associated 2 2.4619
HBB hemoglobin, beta 2.41052
PCSK2 proprotein convertase subtilisin/kexin type 2 2.3394
DDR1 discoidin domain receptor tyrosine kinase 1 2.30982
CAPN1 calpain 1, (mu/I) large subunit 2.29165
APIP APAF1 interacting protein 2.1356
SNAP91 synaptosomal-associated protein, 91kDa 2.06785
PDLIM1 PDZ and LIM domain 1 2.01055

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -5.3439
SLC35F2 solute carrier family 35, member F2 -5.17145
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -5.1059
PCCB propionyl CoA carboxylase, beta polypeptide -4.5048
ADI1 acireductone dioxygenase 1 -4.2676
PMM2 phosphomannomutase 2 -4.0497
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.87675
ELAC2 elaC ribonuclease Z 2 -3.8162
SGK1 serum/glucocorticoid regulated kinase 1 -3.13835
KDM3A lysine (K)-specific demethylase 3A -2.97455
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.94325
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.23537
TSPAN3 tetraspanin 3 -2.23263
RUVBL1 RuvB-like AAA ATPase 1 -2.1597