CRCGN015_MCF10A.TP53.M_24H:K24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(2-chloroethyl) phosphate 11.14 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.8297
ZMIZ1 zinc finger, MIZ-type containing 1 3.00025
GET1 guided entry of tail-anchored proteins factor 1 2.8595
LYRM1 LYR motif containing 1 2.50015
NCK1 NCK adaptor protein 1 2.4091
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 2.3316
CREG1 cellular repressor of E1A-stimulated genes 1 2.0509
HMOX1 heme oxygenase 1 2.03125

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -5.09652
TXNDC9 thioredoxin domain containing 9 -4.88482
UBE3C ubiquitin protein ligase E3C -3.9187
MSMO1 methylsterol monooxygenase 1 -3.64935
RPS5 ribosomal protein S5 -3.07285
NVL nuclear VCP-like -3.0521
SOAT2 sterol O-acyltransferase 2 -2.99158
BASP1 brain abundant, membrane attached signal protein 1 -2.78205
STXBP2 syntaxin binding protein 2 -2.60425
PIH1D1 PIH1 domain containing 1 -2.4585
PDCL3 phosducin-like 3 -2.3113
SCG5 secretogranin V -2.24065
CHST10 carbohydrate sulfotransferase 10 -2.2258
MYLK myosin light chain kinase -2.17455
FCMR Fc fragment of IgM receptor -2.08922
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.04455