| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | aflatoxin-b1 32.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRR7 | proline rich 7 (synaptic) | 4.45166 |
| MCOLN1 | mucolipin 1 | 4.4416 |
| BCL7B | B-cell CLL/lymphoma 7B | 3.66563 |
| MAP7 | microtubule-associated protein 7 | 3.63966 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 3.36544 |
| E2F2 | E2F transcription factor 2 | 3.2984 |
| RPL39L | ribosomal protein L39-like | 3.14399 |
| LGMN | legumain | 2.9045 |
| MSRA | methionine sulfoxide reductase A | 2.8289 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.8125 |
| TXNL4B | thioredoxin-like 4B | 2.75911 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.72632 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 2.67008 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.57782 |
| TCEA2 | transcription elongation factor A (SII), 2 | 2.55211 |
| PTGFR | prostaglandin F receptor (FP) | 2.50153 |
| OCLN | occludin | 2.37149 |
| CMTR1 | cap methyltransferase 1 | 2.34446 |
| SPAG4 | sperm associated antigen 4 | 2.29189 |
| FUS | FUS RNA binding protein | 2.29004 |
| INTS3 | integrator complex subunit 3 | 2.28346 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 2.27632 |
| NUCB2 | nucleobindin 2 | 2.22458 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 2.18848 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 2.15553 |
| WASF3 | WAS protein family, member 3 | 2.12516 |
| OXR1 | oxidation resistance 1 | 2.10909 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 2.04289 |
| CPT1B | carnitine palmitoyltransferase 1B (muscle) | 2.04143 |
| LILRB5 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 | 2.04009 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 2.00065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF20A | kinesin family member 20A | -4.54655 |
| THAP11 | THAP domain containing 11 | -4.34754 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.2098 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -4.14921 |
| PCNA | proliferating cell nuclear antigen | -3.70693 |
| KIF14 | kinesin family member 14 | -3.59587 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -3.59307 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -3.54189 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.93273 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.85626 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -2.72682 |
| TRIB3 | tribbles pseudokinase 3 | -2.71977 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -2.71677 |
| HMG20B | high mobility group 20B | -2.64565 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -2.50453 |
| KIF18A | kinesin family member 18A | -2.48103 |
| COG2 | component of oligomeric golgi complex 2 | -2.33355 |
| FADD | Fas (TNFRSF6)-associated via death domain | -2.32769 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.28385 |
| COQ9 | coenzyme Q9 | -2.23877 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.19896 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -2.15731 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -2.13576 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -2.0595 |
| TNIP1 | TNFAIP3 interacting protein 1 | -2.00999 |
| CORO1A | coronin, actin binding protein, 1A | -2.00861 |
