CRCGN015_MCF10A.TP53.M_24H:L04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-phenyl-p-phenylenediamine.hcl 98.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

528 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 10.0
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 10.0
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 9.16039
TXNRD1 thioredoxin reductase 1 8.2304
GLRX glutaredoxin (thioltransferase) 7.57483
NUCB2 nucleobindin 2 7.3695
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 7.26699
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.47875
AARS1 alanyl-tRNA synthetase 1 6.41547
AGR2 anterior gradient 2 6.38213
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 6.03922
COMP cartilage oligomeric matrix protein 6.01042
GFPT1 glutamine--fructose-6-phosphate transaminase 1 5.83339
STXBP1 syntaxin binding protein 1 5.81738
SQSTM1 sequestosome 1 5.30471
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.08941
LRP10 low density lipoprotein receptor-related protein 10 4.94496
PYCR1 pyrroline-5-carboxylate reductase 1 4.72452
CTSL cathepsin L 4.66561
CDPF1 cysteine-rich, DPF motif domain containing 1 4.55114
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.45845
LOC128125814 uncharacterized LOC128125814 4.39017
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 4.32082
TRIB3 tribbles pseudokinase 3 4.25499
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.25204
WIF1 WNT inhibitory factor 1 4.23669
PHGDH phosphoglycerate dehydrogenase 4.17955
GSTZ1 glutathione S-transferase zeta 1 4.05679
GARS1 glycyl-tRNA synthetase 1 4.01366
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.95707
TICAM1 toll-like receptor adaptor molecule 1 3.91295
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.89175
UBQLN2 ubiquilin 2 3.88182
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.87956
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.85668
IER3 immediate early response 3 3.85024
GALE UDP-galactose-4-epimerase 3.84208
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3.81234
MAP7 microtubule-associated protein 7 3.77788
SARS1 seryl-tRNA synthetase 1 3.64994
SLC67A1 solute carrier family 67 member 1 3.63846
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 3.54854
GMPPA GDP-mannose pyrophosphorylase A 3.5128
SYNGAP1 synaptic Ras GTPase activating protein 1 3.45491
STAMBP STAM binding protein 3.45175
OXSR1 oxidative stress responsive 1 3.43303
SNX11 sorting nexin 11 3.40035
ARMCX3 armadillo repeat containing, X-linked 3 3.34879
UGDH UDP-glucose 6-dehydrogenase 3.34746
ATF3 activating transcription factor 3 3.344
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.34118
MANF mesencephalic astrocyte-derived neurotrophic factor 3.28577
ABHD4 abhydrolase domain containing 4 3.27238
G0S2 G0/G1 switch 2 3.23354
VAT1 vesicle amine transport 1 3.23171
RGS2 regulator of G-protein signaling 2 3.22901
ECM1 extracellular matrix protein 1 3.18769
VGLL4 vestigial-like family member 4 3.18126
ATF4 activating transcription factor 4 3.17348
EGR1 early growth response 1 3.13402
DUSP4 dual specificity phosphatase 4 3.1331
CCNA1 cyclin A1 3.12401
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.09899
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.09762
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.0811
NPC1 Niemann-Pick disease, type C1 3.07809
NFE2L1 nuclear factor, erythroid 2-like 1 3.06944
VSIG2 V-set and immunoglobulin domain containing 2 3.0426
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.02399
PSAT1 phosphoserine aminotransferase 1 2.9498
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.9447
CARS1 cysteinyl-tRNA synthetase 1 2.91962
RAP1GAP RAP1 GTPase activating protein 2.87187
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.86484
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.86068
CHIC2 cysteine-rich hydrophobic domain 2 2.82493
MAMLD1 mastermind-like domain containing 1 2.82157
STC2 stanniocalcin 2 2.80438
WFS1 Wolfram syndrome 1 (wolframin) 2.77919
IRF9 interferon regulatory factor 9 2.77487
MVP major vault protein 2.76423
GTPBP2 GTP binding protein 2 2.76421
NDEL1 nudE neurodevelopment protein 1-like 1 2.7455
PYGB phosphorylase, glycogen; brain 2.73706
YARS1 tyrosyl-tRNA synthetase 1 2.71416
TPM1 tropomyosin 1 (alpha) 2.7039
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.68804
LOC128125822 uncharacterized LOC128125822 2.64663
AXIN1 axin 1 2.62822
RHOF ras homolog family member F (in filopodia) 2.59707
TARS1 threonyl-tRNA synthetase 1 2.5766
ALAS1 5'-aminolevulinate synthase 1 2.56817
ASL argininosuccinate lyase 2.55595
MLPH melanophilin 2.55392
NUPR1 nuclear protein, transcriptional regulator, 1 2.54931
GBA1 glucosylceramidase beta 1 2.54219
CAMTA2 calmodulin binding transcription activator 2 2.54181
ELOVL1 ELOVL fatty acid elongase 1 2.53476
MYH9 myosin, heavy chain 9, non-muscle 2.53127
MID1IP1 MID1 interacting protein 1 2.52567
EEIG1 estrogen-induced osteoclastogenesis regulator 1 2.51538
MCUR1 mitochondrial calcium uniporter regulator 1 2.5132
COPZ2 coatomer protein complex, subunit zeta 2 2.511
AVPI1 arginine vasopressin-induced 1 2.4949
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.48825
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2.4882
MICALL1 MICAL-like 1 2.4794
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.47254
DUSP5 dual specificity phosphatase 5 2.47083
ARMCX6 armadillo repeat containing, X-linked 6 2.46783
TES testin LIM domain protein 2.45765
SLC35B1 solute carrier family 35, member B1 2.45153
IFRD1 interferon-related developmental regulator 1 2.44659
ACBD3 acyl-CoA binding domain containing 3 2.44625
RNF103 ring finger protein 103 2.42866
RRAS related RAS viral (r-ras) oncogene homolog 2.41216
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.40729
PLK3 polo-like kinase 3 2.40443
BCL2L2 BCL2-like 2 2.40057
HYOU1 hypoxia up-regulated 1 2.39082
IRF7 interferon regulatory factor 7 2.38611
ERP29 endoplasmic reticulum protein 29 2.38118
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.37709
ACAA1 acetyl-CoA acyltransferase 1 2.37504
HS1BP3 HCLS1 binding protein 3 2.34678
XPOT exportin, tRNA 2.34641
PNKP polynucleotide kinase 3'-phosphatase 2.3372
METRN meteorin, glial cell differentiation regulator 2.33034
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.32614
FHL2 four and a half LIM domains 2 2.31363
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.31278
FOXO4 forkhead box O4 2.29901
HBEGF heparin-binding EGF-like growth factor 2.28677
GPC1 glypican 1 2.2867
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.28602
ISG15 ISG15 ubiquitin-like modifier 2.28454
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.28418
HMGA2 high mobility group AT-hook 2 2.28053
IFI6 interferon, alpha-inducible protein 6 2.27589
UPP1 uridine phosphorylase 1 2.27562
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.25736
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.24073
TP53BP2 tumor protein p53 binding protein 2 2.23748
INO80B INO80 complex subunit B 2.23233
MUTYH mutY homolog 2.2274
FN1 fibronectin 1 2.21946
CEMIP2 cell migration inducing hyaluronidase 2 2.21759
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.21704
TNIP1 TNFAIP3 interacting protein 1 2.21565
GABARAPL1 GABA(A) receptor-associated protein like 1 2.19826
FLNB filamin B, beta 2.19145
HSPB1 heat shock 27kDa protein 1 2.18909
GPR137B G protein-coupled receptor 137B 2.18404
FAM50A family with sequence similarity 50, member A 2.18279
ODR4 odr-4 GPCR localization factor homolog 2.18268
ACTC1 actin, alpha, cardiac muscle 1 2.18164
COL9A3 collagen, type IX, alpha 3 2.17906
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.14528
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.13706
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.13487
MINDY1 MINDY lysine 48 deubiquitinase 1 2.13484
TUFT1 tuftelin 1 2.13215
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.12845
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.12755
LPXN leupaxin 2.12591
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.1119
PLAAT3 phospholipase A and acyltransferase 3 2.1114
TSG101 tumor susceptibility 101 2.10752
CALCOCO2 calcium binding and coiled-coil domain 2 2.10308
MACO1 macoilin 1 2.10078
DIXDC1 DIX domain containing 1 2.10066
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.09637
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.09108
ELL2 elongation factor, RNA polymerase II, 2 2.0854
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.0846
STX4 syntaxin 4 2.07919
TALDO1 transaldolase 1 2.07567
KEAP1 kelch-like ECH-associated protein 1 2.07005
VRK2 vaccinia related kinase 2 2.06352
DUSP10 dual specificity phosphatase 10 2.06244
FLCN folliculin 2.06106
ACOT13 acyl-CoA thioesterase 13 2.06032
CLIC3 chloride intracellular channel 3 2.05347
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.04834
GADD45A growth arrest and DNA-damage-inducible, alpha 2.0459
GSK3B glycogen synthase kinase 3 beta 2.03803
MEF2D myocyte enhancer factor 2D 2.03077
STYXL1 serine/threonine/tyrosine interacting-like 1 2.02176
FNDC4 fibronectin type III domain containing 4 2.01951
MTMR11 myotubularin related protein 11 2.0055
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.00065

decreased expression

Symbol Name Standardized Value
DSG2 desmoglein 2 -6.98756
ANKRD10 ankyrin repeat domain 10 -6.83021
STMN1 stathmin 1 -6.72677
KIF20A kinesin family member 20A -6.04625
TCERG1 transcription elongation regulator 1 -6.00744
BID BH3 interacting domain death agonist -5.75269
MCM3 minichromosome maintenance complex component 3 -5.32509
NT5DC2 5'-nucleotidase domain containing 2 -5.25274
THAP11 THAP domain containing 11 -5.17028
CDK4 cyclin-dependent kinase 4 -5.0708
BIRC5 baculoviral IAP repeat containing 5 -5.05483
GRWD1 glutamate-rich WD repeat containing 1 -5.01609
HOXA5 homeobox A5 -4.9237
PCNA proliferating cell nuclear antigen -4.89058
CCNB2 cyclin B2 -4.80809
CDC45 cell division cycle 45 -4.80364
DCK deoxycytidine kinase -4.6545
TOP2A topoisomerase (DNA) II alpha 170kDa -4.42392
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.27701
TXNDC9 thioredoxin domain containing 9 -3.86654
APIP APAF1 interacting protein -3.84766
TOPBP1 topoisomerase (DNA) II binding protein 1 -3.84196
SDHAF3 succinate dehydrogenase complex assembly factor 3 -3.82528
NEK2 NIMA-related kinase 2 -3.81921
CYCS cytochrome c, somatic -3.81899
NUSAP1 nucleolar and spindle associated protein 1 -3.79783
ASF1B anti-silencing function 1B histone chaperone -3.75743
CCNA2 cyclin A2 -3.69393
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.65293
PSRC1 proline/serine-rich coiled-coil 1 -3.55869
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.55844
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.52583
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.47357
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.46084
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.46072
KIF14 kinesin family member 14 -3.45269
NAT10 N-acetyltransferase 10 (GCN5-related) -3.40726
NUP133 nucleoporin 133kDa -3.39698
PLK1 polo-like kinase 1 -3.33738
DEPDC1 DEP domain containing 1 -3.28647
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.27259
FBXO5 F-box protein 5 -3.27248
PARPBP PARP1 binding protein -3.24541
NUP93 nucleoporin 93kDa -3.22877
CKAP2 cytoskeleton associated protein 2 -3.21458
CDC23 cell division cycle 23 -3.21145
OIP5 Opa interacting protein 5 -3.20819
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.20029
CD320 CD320 molecule -3.19986
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -3.19563
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.19451
TMEM109 transmembrane protein 109 -3.17498
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.1719
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.1702
CCNF cyclin F -3.13703
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -3.13318
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.12652
RECQL RecQ helicase-like -3.1222
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -3.11745
MANEA mannosidase, endo-alpha -3.09821
CDK1 cyclin-dependent kinase 1 -3.08363
KIF18A kinesin family member 18A -3.06707
RFC2 replication factor C (activator 1) 2, 40kDa -3.05074
YEATS4 YEATS domain containing 4 -3.04565
SPC25 SPC25, NDC80 kinetochore complex component -3.03576
KIF11 kinesin family member 11 -3.03095
PARP1 poly (ADP-ribose) polymerase 1 -3.02507
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.01438
CDC20 cell division cycle 20 -3.00454
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.00033
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.98693
KIF4A kinesin family member 4A -2.98041
ZFP30 ZFP30 zinc finger protein -2.97379
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.97276
TFDP1 transcription factor Dp-1 -2.94193
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.94181
HADH hydroxyacyl-CoA dehydrogenase -2.88131
HOXA4 homeobox A4 -2.8757
NEMP1 nuclear envelope integral membrane protein 1 -2.87522
ZNF274 zinc finger protein 274 -2.86307
HAT1 histone acetyltransferase 1 -2.8489
EBNA1BP2 EBNA1 binding protein 2 -2.84041
PRPF31 pre-mRNA processing factor 31 -2.83292
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.8244
FEN1 flap structure-specific endonuclease 1 -2.81793
TMEM51 transmembrane protein 51 -2.80716
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.80017
NCAPD2 non-SMC condensin I complex, subunit D2 -2.79909
GOLT1B golgi transport 1B -2.78851
NDC80 NDC80 kinetochore complex component -2.78442
TBC1D10C TBC1 domain family, member 10C -2.7832
CDC25C cell division cycle 25C -2.76444
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.75544
CDC25B cell division cycle 25B -2.75489
BZW2 basic leucine zipper and W2 domains 2 -2.7476
ISOC2 isochorismatase domain containing 2 -2.73966
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.7208
ATF5 activating transcription factor 5 -2.70774
CISD1 CDGSH iron sulfur domain 1 -2.70182
TSFM Ts translation elongation factor, mitochondrial -2.69208
NLGN4X neuroligin 4, X-linked -2.69177
NUP85 nucleoporin 85kDa -2.67444
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.6706
FBXO3 F-box protein 3 -2.66766
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.65955
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.6534
PARP2 poly (ADP-ribose) polymerase 2 -2.65121
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.65057
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.64054
FOXM1 forkhead box M1 -2.63667
PGAM4 phosphoglycerate mutase family member 4 -2.63263
MCM6 minichromosome maintenance complex component 6 -2.62337
ZNF813 zinc finger protein 813 -2.61941
ZCCHC10 zinc finger, CCHC domain containing 10 -2.59787
RBL1 retinoblastoma-like 1 -2.59276
CEP192 centrosomal protein 192kDa -2.59081
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.59069
PIMREG PICALM interacting mitotic regulator -2.57886
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.57782
NOP16 NOP16 nucleolar protein -2.56814
TXNL4B thioredoxin-like 4B -2.56452
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.56426
IPO8 importin 8 -2.55812
MPHOSPH9 M-phase phosphoprotein 9 -2.55561
PBK PDZ binding kinase -2.55263
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.55187
UBA2 ubiquitin-like modifier activating enzyme 2 -2.54784
CLTB clathrin, light chain B -2.5478
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.52678
GTF2A2 general transcription factor IIA, 2, 12kDa -2.52636
SRSF2 serine/arginine-rich splicing factor 2 -2.52388
NCAPH non-SMC condensin I complex, subunit H -2.5235
ZNF606 zinc finger protein 606 -2.52025
ZNF45 zinc finger protein 45 -2.5113
GMNN geminin, DNA replication inhibitor -2.51068
ACTL6A actin-like 6A -2.51036
DEK DEK proto-oncogene -2.50085
RPIA ribose 5-phosphate isomerase A -2.49662
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.48909
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.48797
PHB2 prohibitin 2 -2.48316
PLSCR1 phospholipid scramblase 1 -2.48314
FCF1 FCF1 rRNA-processing protein -2.48297
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.47805
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.4746
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.47284
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.47009
AURKA aurora kinase A -2.46522
TMX1 thioredoxin-related transmembrane protein 1 -2.4531
MCMBP minichromosome maintenance complex binding protein -2.45081
VRK1 vaccinia related kinase 1 -2.449
F2R coagulation factor II (thrombin) receptor -2.44794
HDAC2 histone deacetylase 2 -2.44602
ZNF143 zinc finger protein 143 -2.44379
RRP1B ribosomal RNA processing 1B -2.44294
BBS10 Bardet-Biedl syndrome 10 -2.44195
RMI1 RecQ mediated genome instability 1 -2.43812
ZNF629 zinc finger protein 629 -2.4353
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.43501
CDCA8 cell division cycle associated 8 -2.43335
ZMYM1 zinc finger, MYM-type 1 -2.42866
HOXA2 homeobox A2 -2.42502
DNM1 dynamin 1 -2.42242
ZNF329 zinc finger protein 329 -2.41825
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.41539
COMMD9 COMM domain containing 9 -2.41279
ANAPC15 anaphase promoting complex subunit 15 -2.40003
FBL fibrillarin -2.39733
ADI1 acireductone dioxygenase 1 -2.39694
CPNE3 copine III -2.3962
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -2.3938
ARHGAP11A Rho GTPase activating protein 11A -2.39139
SMC4 structural maintenance of chromosomes 4 -2.38021
MCM9 minichromosome maintenance complex component 9 -2.36624
ATP5F1B ATP synthase F1 subunit beta -2.36147
IMPACT impact RWD domain protein -2.3614
DSN1 DSN1, MIS12 kinetochore complex component -2.35503
CXCR1 chemokine (C-X-C motif) receptor 1 -2.35451
TATDN2 TatD DNase domain containing 2 -2.35337
TMEM123 transmembrane protein 123 -2.35071
FKBP5 FK506 binding protein 5 -2.34298
REV1 REV1, polymerase (DNA directed) -2.33884
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.33869
CDCA3 cell division cycle associated 3 -2.31596
SMNDC1 survival motor neuron domain containing 1 -2.30876
MSH2 mutS homolog 2 -2.30474
CENPA centromere protein A -2.29279
PHKG2 phosphorylase kinase, gamma 2 (testis) -2.28045
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.27719
CS citrate synthase -2.2769
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.2767
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.27516
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -2.27344
WDR76 WD repeat domain 76 -2.27269
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.27054
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.27002
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.26872
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.26574
SYNJ2BP synaptojanin 2 binding protein -2.26442
MFAP3 microfibrillar-associated protein 3 -2.26346
CDH10 cadherin 10, type 2 (T2-cadherin) -2.26108
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.25743
LHX6 LIM homeobox 6 -2.25549
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.2543
BRCA1 breast cancer 1, early onset -2.25315
CAPRIN1 cell cycle associated protein 1 -2.24908
PA2G4 proliferation-associated 2G4, 38kDa -2.24541
PRPF4B pre-mRNA processing factor 4B -2.23668
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -2.23648
LBR lamin B receptor -2.23305
RAD51AP1 RAD51 associated protein 1 -2.23183
DPY19L1 dpy-19-like 1 (C. elegans) -2.22173
KIF15 kinesin family member 15 -2.22043
KRT13 keratin 13, type I -2.21883
SNRPF small nuclear ribonucleoprotein polypeptide F -2.2179
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.21394
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.2135
ZSCAN5A zinc finger and SCAN domain containing 5A -2.20526
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.20498
SOCS5 suppressor of cytokine signaling 5 -2.20153
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.20028
NEK4 NIMA-related kinase 4 -2.1996
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.1939
FJX1 four jointed box 1 (Drosophila) -2.18076
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.16831
MRPL11 mitochondrial ribosomal protein L11 -2.16739
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -2.1672
ERCC6L excision repair cross-complementation group 6-like -2.16521
COMMD8 COMM domain containing 8 -2.16509
CDT1 chromatin licensing and DNA replication factor 1 -2.16486
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.16407
TROAP trophinin associated protein -2.16253
QSER1 glutamine and serine rich 1 -2.16238
SPDL1 spindle apparatus coiled-coil protein 1 -2.16117
NASP nuclear autoantigenic sperm protein (histone-binding) -2.16067
WRAP53 WD repeat containing, antisense to TP53 -2.15809
LRRC40 leucine rich repeat containing 40 -2.15748
INTS8 integrator complex subunit 8 -2.156
SCML2 sex comb on midleg-like 2 (Drosophila) -2.15515
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.15065
USP39 ubiquitin specific peptidase 39 -2.14974
CDC6 cell division cycle 6 -2.14962
NPM3 nucleophosmin/nucleoplasmin 3 -2.14919
PRMT3 protein arginine methyltransferase 3 -2.14433
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -2.14354
SNRPC small nuclear ribonucleoprotein polypeptide C -2.14291
NHLRC2 NHL repeat containing 2 -2.14154
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.13938
CDC7 cell division cycle 7 -2.13697
CBX3 chromobox homolog 3 -2.1361
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.13339
THNSL1 threonine synthase-like 1 (S. cerevisiae) -2.13317
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.13147
SESN1 sestrin 1 -2.13142
CCNB1 cyclin B1 -2.1312
ZNF180 zinc finger protein 180 -2.13045
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.13042
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.12778
MRTFB myocardin related transcription factor B -2.12757
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.12756
TSPAN6 tetraspanin 6 -2.12745
POLR1F RNA polymerase I subunit F -2.12225
TWSG1 twisted gastrulation BMP signaling modulator 1 -2.11404
LZTFL1 leucine zipper transcription factor-like 1 -2.11052
RFC3 replication factor C (activator 1) 3, 38kDa -2.10878
RBMX RNA binding motif protein, X-linked -2.1072
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.10717
INTS9 integrator complex subunit 9 -2.10605
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.10312
UNC119B unc-119 homolog B (C. elegans) -2.10295
INCENP inner centromere protein antigens 135/155kDa -2.10277
TRAPPC13 trafficking protein particle complex 13 -2.10159
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.10119
NUP107 nucleoporin 107kDa -2.0981
TRAP1 TNF receptor-associated protein 1 -2.09717
GTPBP8 GTP-binding protein 8 (putative) -2.09557
ATG5 autophagy related 5 -2.09459
AIRIM AFG2 interacting ribosome maturation factor -2.0941
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.09154
TRIM28 tripartite motif containing 28 -2.09032
FHL5 four and a half LIM domains 5 -2.08996
KRT14 keratin 14, type I -2.08776
HIKESHI heat shock protein nuclear import factor hikeshi -2.08754
GEMIN2 gem (nuclear organelle) associated protein 2 -2.08733
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.08725
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.08714
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.08699
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.08686
BPHL biphenyl hydrolase-like (serine hydrolase) -2.08681
KRTAP5-2 keratin associated protein 5-2 -2.08459
PARG poly (ADP-ribose) glycohydrolase -2.0836
CAVIN2 caveolae associated protein 2 -2.08195
IPO9 importin 9 -2.0797
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.07631
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.07597
CENPQ centromere protein Q -2.07501
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.07216
MATR3 matrin 3 -2.06897
FBXO38 F-box protein 38 -2.06671
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.0661
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.06463
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.06259
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.05811
ERCC3 excision repair cross-complementation group 3 -2.05475
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.05365
CEP76 centrosomal protein 76kDa -2.0527
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -2.05213
ECSIT ECSIT signalling integrator -2.05103
DBF4 DBF4 zinc finger -2.05087
ZNF318 zinc finger protein 318 -2.04467
ZNF551 zinc finger protein 551 -2.04132
FFAR2 free fatty acid receptor 2 -2.04062
UXT ubiquitously-expressed, prefoldin-like chaperone -2.03729
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.03615
GDE1 glycerophosphodiester phosphodiesterase 1 -2.03058
ZNF510 zinc finger protein 510 -2.02908
HMGB2 high mobility group box 2 -2.02651
TMEM177 transmembrane protein 177 -2.02635
CHURC1-FNTB CHURC1-FNTB readthrough -2.02568
PRUNE1 prune exopolyphosphatase 1 -2.02557
PRCP prolylcarboxypeptidase (angiotensinase C) -2.02528
YIPF5 Yip1 domain family, member 5 -2.02415
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -2.02085
CIRBP cold inducible RNA binding protein -2.02023
RAB33B RAB33B, member RAS oncogene family -2.01941
NDC1 NDC1 transmembrane nucleoporin -2.01438
IPO5 importin 5 -2.01291
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.01134
EXT2 exostosin glycosyltransferase 2 -2.00997
ATP5F1A ATP synthase F1 subunit alpha -2.00869
RFWD3 ring finger and WD repeat domain 3 -2.0084
MTOR mechanistic target of rapamycin (serine/threonine kinase) -2.00514
LIFR leukemia inhibitory factor receptor alpha -2.00316
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.00282
EDNRB endothelin receptor type B -2.00226
PTPRJ protein tyrosine phosphatase, receptor type, J -2.00204
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.0007