| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-phenyl-p-phenylenediamine.hcl 32.93 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.16895 |
| SPAG4 | sperm associated antigen 4 | 4.10671 |
| WIF1 | WNT inhibitory factor 1 | 3.98395 |
| NUCB2 | nucleobindin 2 | 3.61134 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 3.56811 |
| MYLK | myosin light chain kinase | 3.15078 |
| GATA2 | GATA binding protein 2 | 3.08442 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.01827 |
| LGMN | legumain | 2.61937 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.47255 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.41831 |
| CLBA1 | clathrin binding box of aftiphilin containing 1 | 2.32548 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 2.31084 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.29015 |
| PFDN1 | prefoldin subunit 1 | 2.27874 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | 2.23911 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 2.22599 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 | 2.21625 |
| LOX | lysyl oxidase | 2.21047 |
| UIMC1 | ubiquitin interaction motif containing 1 | 2.20774 |
| CCDC85B | coiled-coil domain containing 85B | 2.18333 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 2.11548 |
| HINT1 | histidine triad nucleotide binding protein 1 | 2.11049 |
| PRR7 | proline rich 7 (synaptic) | 2.0842 |
| SEMA6C | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C | 2.05811 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 2.05509 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.02976 |
| IFT81 | intraflagellar transport 81 | 2.02045 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 2.01831 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 2.01745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ANKRD10 | ankyrin repeat domain 10 | -6.72659 |
| PLK1 | polo-like kinase 1 | -5.6482 |
| CCNB1 | cyclin B1 | -5.52718 |
| CDC25B | cell division cycle 25B | -4.96301 |
| HMG20B | high mobility group 20B | -4.52013 |
| CDC20 | cell division cycle 20 | -4.44168 |
| CYCS | cytochrome c, somatic | -4.19452 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.76206 |
| KRT14 | keratin 14, type I | -3.12558 |
| RPIA | ribose 5-phosphate isomerase A | -2.92805 |
| CHMP4B | charged multivesicular body protein 4B | -2.92001 |
| CDCA8 | cell division cycle associated 8 | -2.9105 |
| TSPAN4 | tetraspanin 4 | -2.86024 |
| NGRN | neugrin, neurite outgrowth associated | -2.76918 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -2.76522 |
| RPS5 | ribosomal protein S5 | -2.66936 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.63108 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -2.62657 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.62602 |
| DEPDC1 | DEP domain containing 1 | -2.60543 |
| HEATR1 | HEAT repeat containing 1 | -2.60315 |
| HAT1 | histone acetyltransferase 1 | -2.54961 |
| GTSE1 | G-2 and S-phase expressed 1 | -2.4536 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -2.3568 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.35283 |
| NEK2 | NIMA-related kinase 2 | -2.34252 |
| CAPN2 | calpain 2, (m/II) large subunit | -2.33299 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -2.25824 |
| PTK2 | protein tyrosine kinase 2 | -2.25115 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -2.14902 |
| ART3 | ADP-ribosyltransferase 3 | -2.14589 |
| EN1 | engrailed homeobox 1 | -2.09916 |
| CCL23 | chemokine (C-C motif) ligand 23 | -2.09287 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -2.08434 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.07268 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.01963 |
| CD58 | CD58 molecule | -2.01889 |
| PAQR5 | progestin and adipoQ receptor family member V | -2.01438 |
| KIF2C | kinesin family member 2C | -2.00508 |
| TTC19 | tetratricopeptide repeat domain 19 | -2.0009 |
